Genome-wide assessment of genetic diversity and population structure insights into admixture and introgression in Chinese indigenous cattle

Zhang, Wengang; Gao, Xue; Zhang, Yang; Zhao, Yumin; Zhang, Jiabao; Jia, Yutang; Zhu, Bo; Xu, Lingyang; Zhang, Lupei; Gao, Huijiang; Li, Junya; Chen, Yan

doi:10.1186/s12863-018-0705-9

Cited by 42 publications

(37 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The south-east had higher environmental parameters than any other region followed by the south-west. Also, the lineage of southern Chinese cattle was mainly indicine [41][42][43][44] in areas whose values of T, RH, and THI were significantly (p < 0.01) higher than those that had genotype AA. Based on these findings, the mutation for the HSF1 gene was associated with heat tolerance, which might be useful for marker-assisted selection of cattle.…”

Section: Discussionmentioning

confidence: 93%

Association of HSF1 Genetic Variation with Heat Tolerance in Chinese Cattle

Rao

Zeng

Guan

et al. 2019

Animals

View full text Add to dashboard Cite

The heat shock factor 1 (HSF1) gene is a regulator of the heat stress response, maximizing HSP protein expression survival. In this research, we explored the frequency distribution of a missense mutation (NC_037341.1 g.616087A > G, rs135258919) in the HSF1 gene in Chinese cattle with amino acid substitution, valine to alanine. This mutation could be related to the heat tolerance in Bos indicus. A total of 941 individuals representing 35 Chinese native cattle breeds, combining pure taurine (Angus) and indicine cattle, were used to determine the genotypes of the mutation through PCR and partial DNA sequencing. The results showed significant differences in allele frequencies and their genotypes amongst Chinese cattle from different regions. Allele G or indicine-specific allele frequency diminished from south to north China, while allele A (genotype AA) or the taurine-specific allele had a contrary pattern, which agreed with the distribution of taurine and indicine cattle. According to the association analysis, the NC_037341.1 g.616087A > G (rs135258919) of the bovine HSF1 gene, annual temperature (T), relative humidity (RH), and the temperature humidity index (THI) (p < 0.01) were interrelated closely, which indicated that the NC_037341.1 g.616087A > G of the HSF1 gene is associated with heat tolerance in indicine cattle.

show abstract

Section: Discussionmentioning

confidence: 93%

Association of HSF1 Genetic Variation with Heat Tolerance in Chinese Cattle

Rao

Zeng

Guan

et al. 2019

Animals

View full text Add to dashboard Cite

show abstract

“…Another dairy breed, the hardy Scottish Ayrshire, had a major influence on several Norwegian, Swedish and Finnish breeds (Li & Kantanen 2010), whereas modern dairy breeds have been crossed into Danish Red (Zhang et al . 2018a, 2018b). The dispersal of these dairy breeds largely accounts for the north‐west European range of the Y‐chromosomal haplogroup Y1.…”

Section: Domestication Dispersal and Differentiation Of Breedsmentioning

confidence: 99%

“…2018; Zhang et al . 2018a, 2018b), including Siberia, with its extremes of temperature (Iso‐Touru et al . 2016).…”

Section: Domestication Dispersal and Differentiation Of Breedsmentioning

confidence: 99%

Evolution and domestication of the Bovini species

et al. 2020

View full text Add to dashboard Cite

Summary Domestication of the Bovini species (taurine cattle, zebu, yak, river buffalo and swamp buffalo) since the early Holocene (ca. 10 000 BCE) has contributed significantly to the development of human civilization. In this study, we review recent literature on the origin and phylogeny, domestication and dispersal of the three major Bos species – taurine cattle, zebu and yak – and their genetic interactions. The global dispersion of taurine and zebu cattle was accompanied by population bottlenecks, which resulted in a marked phylogeographic differentiation of the mitochondrial and Y‐chromosomal DNA. The high diversity of European breeds has been shaped through isolation‐by‐distance, different production objectives, breed formation and the expansion of popular breeds. The overlapping and broad ranges of taurine and zebu cattle led to hybridization with each other and with other bovine species. For instance, Chinese gayal carries zebu mitochondrial DNA; several Indonesian zebu descend from zebu bull × banteng cow crossings; Tibetan cattle and yak have exchanged gene variants; and about 5% of the American bison contain taurine mtDNA. Analysis at the genomic level indicates that introgression may have played a role in environmental adaptation.

show abstract

“…Hybridisation between taurine and indicine breeds could have contributed to HKF diversity. Both taurine and indicine ancestry have contributed to Chinese cattle genetics, with Northern Chinese breeds having a higher taurine component than Southern breeds which have a greater indicine component (Figs 2-4) [22,43,44]. This is also reflected in mitochondrial data, [22,[45][46][47].…”

Section: Diversity and Structurementioning

confidence: 99%

A genetically unique Chinese cattle population shows evidence of common ancestry with wild species when analysed with a reduced ascertainment bias SNP panel

et al. 2020

View full text Add to dashboard Cite

In Hong Kong, there is a cattle population of~1,200 individuals of uncertain origin and genetic diversity. This population shows heterogeneous morphology, both in body type and pigmentation. Once used as draught animals by the local farmers, they were abandoned around the 1970s due to changes in the economy, and since then have lived as feral populations. To explore the origins of these cattle, we analysed~50k genotype data of 21 Hong Kong feral cattle, along with data from 703 individuals of 36 cattle populations of European, African taurine, and Asian origin, the wild x domestic hybrid gayal, plus two wild bovine species, gaur and banteng. To reduce the effect of ascertainment bias~4k loci that are polymorphic in the two wild species were selected for further analysis. The stringent SNP selection we applied resulted in increased heterozygosity across all populations studies, compared with the full panel of SNP, thus reducing the impact of ascertainment bias and facilitating the comparison of divergent breeds of cattle. Our results showed that Hong Kong feral cattle have relatively high levels of genetic distinctiveness, possibly due to the low level of artificial selection, and a likely common ancestry with wild species. We found signs of a putative taurine introgression, probably dating to the import of north European breeds during the British colonialism of Hong Kong. We showed that Hong Kong feral cattle, are distinct from Bos taurus and Bos indicus breeds. Our results highlight the distinctiveness of Hong Kong feral cattle and stress the conservation value of this indigenous breed that is likely to harbour adaptive genetic variation, which is a fundamental livestock resource in the face of climate change and diversifying market demands.

show abstract

Genome-wide assessment of genetic diversity and population structure insights into admixture and introgression in Chinese indigenous cattle

Cited by 42 publications

References 37 publications

Association of HSF1 Genetic Variation with Heat Tolerance in Chinese Cattle

Association of HSF1 Genetic Variation with Heat Tolerance in Chinese Cattle

Evolution and domestication of the Bovini species

A genetically unique Chinese cattle population shows evidence of common ancestry with wild species when analysed with a reduced ascertainment bias SNP panel

Contact Info

Product

Resources

About