2019
DOI: 10.1016/j.scitotenv.2019.03.110
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Genomic analysis of methicillin-resistant Staphylococcus aureus isolated from poultry and occupational farm workers in Umgungundlovu District, South Africa

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Cited by 36 publications
(37 citation statements)
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“…This has been reported in many species, including Acinetobacter baumannii [70]. Furthermore, core genome phylogenetics, combined with metadata analysis, provided useful insights into the slight distinctions (replicons and insertion sequences) between the CRKP isolates ( Figure 2b) [71]. This is possibly associated with variations in the common genetic backbone of the bla NDM-1, supporting its versatility via a local horizontal transfer and subsequent evolution in their host by recombination events [72,73].…”
Section: Discussionsupporting
confidence: 55%
“…This has been reported in many species, including Acinetobacter baumannii [70]. Furthermore, core genome phylogenetics, combined with metadata analysis, provided useful insights into the slight distinctions (replicons and insertion sequences) between the CRKP isolates ( Figure 2b) [71]. This is possibly associated with variations in the common genetic backbone of the bla NDM-1, supporting its versatility via a local horizontal transfer and subsequent evolution in their host by recombination events [72,73].…”
Section: Discussionsupporting
confidence: 55%
“…Efforts to develop efflux pump inhibitors may mitigate such resistance mechanisms. Resistant S. aureus ST612 ( n = 52), ST239 ( n = 8), ST5 ( n = 60), ST152 ( n = 5), ST45 ( n = 4), ST35 ( n = 4), and ST30 ( n = 3) have been commonly isolated in clinical samples …”
Section: Resultsmentioning
confidence: 99%
“…Moreover, there was limited data on the clinical information, history and/or clinical examination of the patient, and all deposited C. freundii genomes obtained from the human host, which could be very useful in comparative phylogenomic analysis. Ultimately, a combination of demographics, clinical information, Pathogens 2020, 9, 89 7 of 13 and WGS data coupled with graphical analysis should be applied to offer insights into the spread of pathogens and increase confidence during molecular epidemiological investigations [35].…”
Section: Discussionmentioning
confidence: 99%