Genotyping of Chlamydia trachomatis From Endocervical Specimens in Brazil

Abstract

To our knowledge this is the first study to characterize Brazilian C. trachomatis endocervical samples and Brazilian C. trachomatis genotype coinfection. Our results also emphasize the importance of routine diagnosis of C. trachomatis for the control of this STD.

Genotyping and prevalence of Chlamydia trachomatis infection among women in Belém, Pará, northern Brazil

“…Although a large body of work demonstrates the high prevalence of CT infection in the Brazilian population, only two studies describe the distribution of urogenital C. trachomatis genotypes in the midwestern and southeastern regions of the country [15,22]. To our knowledge, this is the first study to describe the genotypic diversity of C. trachomatis associated with genital infection within a population residing in the northern of the country.…”

“…It found four genotypes. At 33.3% each, E and D were the most frequently detected, followed by F and K, which each showed a frequency of 16.7% [15] A broader study by Machado et al (2011) genotyped 163 positive C. trachomatis samples from men and women in two regions of Brazil: the midwestern city of Goiania and the southeastern city of Vitoria. In this study, nine distinct genotypes were encountered, the five most common being E (39.3%), F (16.6%), D (15.9%), I (8.6) and J (7.4%) [22].…”

“…However, isolated studies carried out in this country have shown infection rates ranging from 6% to 31% among women [13,14]. The large range of reported rates reflects discrepancies in both methods used and populations evaluated [15]. Despite a high prevalence of C. trachomatis infection in Brazil, very little is known about the distribution and diversity of genotypes involved in genital infection.…”

Chlamydia trachomatis serotype A infections in the Amazon region of Brazil: prevalence, entry and dissemination

“…The description of serotypes or genotypes of C. trachomatis is not a common procedure, and such analyses are typically focused on strains that are sexually transmitted; this is true for recent reports in Brazil (19) (20) . It is possible that the distribution of different serotypes over the years could have an important clinical impact, although these analyses are almost never performed for strains related to ocular infections.…”

Chlamydia trachomatis Serovar Distribution and Neisseria gonorrhoeae Coinfection in Male Patients with Urethritis in Greece

“…Chlamydia trachomatis is the leading cause of bacterial sexually transmitted diseases (STDs) in industrialized countries, producing infections of the upper and lower genital tract in males and females, including urethritis, epididymitis, and proctitis in males (7,9,14,19). Currently, more than 18 different serovars of the organism have been identified based on conventional serotyping, while more than 29 variants have been recognized by employing monoclonal antibodies or genotypic methods (1,15).…”