Geographic variation in human mitochondrial DNA control region sequence: the population history of Turkey and its relationship to the European populations

Comas, David; Calafell, Francesc; Mateu, Eva; Pérez-Lezaun, Anna; Bertranpetit, Jaume

doi:10.1093/oxfordjournals.molbev.a025669

Cited by 123 publications

(97 citation statements)

References 22 publications

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“…A megalithic at Urfa, East of Turkey, called Göbekli Tepe, confirms hunter-gatherer settlements from 13,000 to 10,000 years old but colonization by modern humans is inferred to have occurred 50,000 years ago from Middle East (Henn et al, 2012). Present Turkish populations show a strong component of "Eastern components" such as so-called D-cluster in mitochondrial diversity analyses (Comas et al, 1996). This admixture may have occurred at several time points, a stronger signal dating from 1,300 A.D. i.e.…”

Section: Turkish History and Emergence Of Tb Tur Sublineagementioning

confidence: 87%

“…tuberculosis phylogeny using the different molecular clocks described in the literature (Bos et al, 2014;Bryant et al, 2013;Comas et al, 2013;Ford et al, 2011;Merker et al, 2015).…”

Section: Discussionmentioning

confidence: 99%

“…S5 in Comas et al 2013). The MRCA reported for the Japanese (T3-Osaka) and Turkish (Tur) was estimated to be approximately 12,000 years old (95% CI 10,907-12,753 years) and the divergence of T3-Osaka isolates potentially corresponding to an epidemic around 7,500 years old ( Fig.…”

Section: Accepted M Manuscriptmentioning

confidence: 97%

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Turkish and Japanese Mycobacterium tuberculosis sublineages share a remote common ancestor

Refrégier

Abadia

Matsumoto

et al. 2016

Infection, Genetics and Evolution

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Section: Turkish History and Emergence Of Tb Tur Sublineagementioning

confidence: 87%

“…tuberculosis phylogeny using the different molecular clocks described in the literature (Bos et al, 2014;Bryant et al, 2013;Comas et al, 2013;Ford et al, 2011;Merker et al, 2015).…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Turkish and Japanese Mycobacterium tuberculosis sublineages share a remote common ancestor

Refrégier

Abadia

Matsumoto

et al. 2016

Infection, Genetics and Evolution

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“…The apportionment for the whole sample set was 0.1170.24 European, 0.4070. 25 Middle Eastern (which adds up to 51% for West Eurasia), 0.4570.05 East Asian, and 0.0470.04 Indian. Although this approach allowed us to use a larger number of parental populations, the standard deviation after 10 000 iterations is extremely high for some of the estimates.…”

Section: Admixture Analysismentioning

confidence: 99%

Admixture, migrations, and dispersals in Central Asia: evidence from maternal DNA lineages

et al. 2004

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“…Both Calafell et al (1996) and Comas et al (1996) have presented data from Turkey. These data suggest the presence of substantial frequencies of cluster H (although lower than that in Europe) (Torroni et al 1998), as well as of I, W, K, and U4, in addition to clusters already identified in the Bedouin.…”

Section: Introductionmentioning

confidence: 99%

Tracing European Founder Lineages in the Near Eastern mtDNA Pool

Richards¹,

Macaulay²,

Hickey³

et al. 2000

Am. J Hum. Genet.

358

548

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Founder analysis is a method for analysis of nonrecombining DNA sequence data, with the aim of identification and dating of migrations into new territory. The method picks out founder sequence types in potential source populations and dates lineage clusters deriving from them in the settlement zone of interest. Here, using mtDNA, we apply the approach to the colonization of Europe, to estimate the proportion of modern lineages whose ancestors arrived during each major phase of settlement. To estimate the Palaeolithic and Neolithic contributions to European mtDNA diversity more accurately than was previously achievable, we have now extended the Near Eastern, European, and northern-Caucasus databases to 1,234, 2,804, and 208 samples, respectively. Both back-migration into the source population and recurrent mutation in the source and derived populations represent major obstacles to this approach. We have developed phylogenetic criteria to take account of both these factors, and we suggest a way to account for multiple dispersals of common sequence types. We conclude that (i) there has been substantial back-migration into the Near East, (ii) the majority of extant mtDNA lineages entered Europe in several waves during the Upper Palaeolithic, (iii) there was a founder effect or bottleneck associated with the Last Glacial Maximum, 20,000 years ago, from which derives the largest fraction of surviving lineages, and (iv) the immigrant Neolithic component is likely to comprise less than one-quarter of the mtDNA pool of modern Europeans.

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Geographic variation in human mitochondrial DNA control region sequence: the population history of Turkey and its relationship to the European populations

Cited by 123 publications

References 22 publications

Turkish and Japanese Mycobacterium tuberculosis sublineages share a remote common ancestor

Turkish and Japanese Mycobacterium tuberculosis sublineages share a remote common ancestor

Admixture, migrations, and dispersals in Central Asia: evidence from maternal DNA lineages

Tracing European Founder Lineages in the Near Eastern mtDNA Pool

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