Geometric Modeling and Finite Element Simulation for Architecture Design of 3D Printed Bio-ceramic Scaffold Used in Bone Tissue Engineering

Bagde, Ashutosh; Kuthe, Abhaykumar M.; Nagdeve, S.; Dahake, Sandeep W.; Sapkal, Pranav S.; Daronde, Subodh; Lande, N. H.; Sarode, Bhupesh

doi:10.1007/s41745-019-00120-0

Cited by 14 publications

(11 citation statements)

References 42 publications

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“…These obtained results are one of the highest reported . Design optimizing using finite element analysis (ANSYS) by Badge et al demonstrated that porosity and mechanical stability of β-TCP scaffolds can be determined by analyzing parameters such as strut width, nozzle diameter, etc . Spoerke et al described the process of formation of organoapatite layers on the porous Ti surface.…”

Section: Designing Using Computational Toolsmentioning

confidence: 99%

“…108 Design optimizing using finite element analysis (ANSYS) by Badge et al demonstrated that porosity and mechanical stability of β-TCP scaffolds can be determined by analyzing parameters such as strut width, nozzle diameter, etc. 109 Spoerke et al described the process of formation of organoapatite layers on the porous Ti surface. FEA has been done to find the bony infiltration in the porous structure, which preserves the life of Ti implant by reducing stress concentration.…”

Section: Materials Involvedmentioning

confidence: 99%

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Comprehensive Review on Design and Manufacturing of Bio-scaffolds for Bone Reconstruction

Ravoor

Thangavel

Elsen

2021

ACS Appl. Bio Mater.

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Bio-scaffolds are synthetic entities widely employed in bone and soft-tissue regeneration applications. These bio-scaffolds are applied to the defect site to provide support and favor cell attachment and growth, thereby enhancing the regeneration of the defective site. The progressive research in bio-scaffold fabrication has led to identification of biocompatible and mechanically stable materials. The difficulties in obtaining grafts and expenditure incurred in the transplantation procedures have also been overcome by the implantation of bio-scaffolds. Drugs, cells, growth factors, and biomolecules can be embedded with bio-scaffolds to provide localized treatments. The right choice of materials and fabrication approaches can help in developing bio-scaffolds with required properties. This review mostly focuses on the available materials and bio-scaffold techniques for bone and soft-tissue regeneration application. The first part of this review gives insight into the various classes of biomaterials involved in bio-scaffold fabrication followed by design and simulation techniques. The latter discusses the various additive, subtractive, hybrid, and other improved techniques involved in the development of bio-scaffolds for bone regeneration applications. Techniques involving multimaterial printing and multidimensional printing have also been briefly discussed.

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Section: Designing Using Computational Toolsmentioning

confidence: 99%

Section: Materials Involvedmentioning

confidence: 99%

Comprehensive Review on Design and Manufacturing of Bio-scaffolds for Bone Reconstruction

Ravoor

Thangavel

Elsen

2021

ACS Appl. Bio Mater.

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“…Additionally, researchers compared description and reproduction procedures based on experience with colour and pattern photographs of demolished archaeological ceramic fragments [25]. ey used the scale invariant function transform (SIFT) and the total variance geometry function identifier (TVG).…”

Section: Background To Modern Ceramic Artmentioning

confidence: 99%

Art Design Teaching Based on the Multidata Fusion Algorithm and Virtual Simulation Technology

Liang

2022

Mobile Information Systems

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Virtual Reality (VR) technologies are widely applied to teaching art design. VR has been created with high-level techniques that create the artificial environment to support virtual aesthetics. Especially ceramics art design requires technical advancement to enhance business individuals. However, the user requires the virtual reality experience to improve the art design teaching performance. During the teaching process, reality learning patterns, experiences, and fusion ceramic product design are required to enhance art design teaching. So, in this research, modern art design has been optimized using virtual reality with a deep learning architecture for craftsmanship, style, ideals, creative aesthetics, cultural ramifications, and inherited designers to create an effective model. The deep learning-assisted gate array algorithm (GAA) is used to optimize the modern art structure in system design. Therefore, this approach reveals some experimental findings that produce better performance benefits than saving time and resources in traditional manual detection systems.

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“…Additionally, it was reported that lattice-based structures with high porosity can effectively mimic bone structure properties [27]. Bagde et al [28] developed a 3D-printed bio-ceramic scaffold used in bone tissue engineering, and its mechanical properties were analysed using FEA. Thirty-six scaffolds with differing geometrical design parameters composed of β-TCP (matrix) reinforced with four different filler materials (zirconium dioxide, magnesium oxide, aluminium oxide, and hydroxyapatite) for extrusion-based 3D bioprinting were used in the simulation.…”

Section: Introductionmentioning

confidence: 99%

“…Thirty-six scaffolds with differing geometrical design parameters composed of β-TCP (matrix) reinforced with four different filler materials (zirconium dioxide, magnesium oxide, aluminium oxide, and hydroxyapatite) for extrusion-based 3D bioprinting were used in the simulation. The results indicated that β-TCP with hydroxyapatite scaffold presented the Young's modulus closely related to natural bone tissue [28]. Patel et al [29] developed a scaffold of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) with a porous architecture, and the mechanical properties were analysed using FEA.…”

Section: Introductionmentioning

confidence: 99%

Mechanical Behaviour Evaluation of Porous Scaffold for Tissue-Engineering Applications Using Finite Element Analysis

et al. 2022

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In recent years, finite element analysis (FEA) models of different porous scaffold shapes consisting of various materials have been developed to predict the mechanical behaviour of the scaffolds and to address the initial goals of 3D printing. Although mechanical properties of polymeric porous scaffolds are determined through FEA, studies on the polymer nanocomposite porous scaffolds are limited. In this paper, FEA with the integration of material designer and representative volume elements (RVE) was carried out on a 3D scaffold model to determine the mechanical properties of boron nitride nanotubes (BNNTs)-reinforced gelatin (G) and alginate (A) hydrogel. The maximum stress regions were predicted by FEA stress distribution. Furthermore, the analysed material model and the boundary conditions showed minor deviation (4%) compared to experimental results. It was noted that the stress regions are detected at the zone close to the pore areas. These results indicated that the model used in this work could be beneficial in FEA studies on 3D-printed porous structures for tissue engineering applications.

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Geometric Modeling and Finite Element Simulation for Architecture Design of 3D Printed Bio-ceramic Scaffold Used in Bone Tissue Engineering

Cited by 14 publications

References 42 publications

Comprehensive Review on Design and Manufacturing of Bio-scaffolds for Bone Reconstruction

Comprehensive Review on Design and Manufacturing of Bio-scaffolds for Bone Reconstruction

Art Design Teaching Based on the Multidata Fusion Algorithm and Virtual Simulation Technology

Mechanical Behaviour Evaluation of Porous Scaffold for Tissue-Engineering Applications Using Finite Element Analysis

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