People’s organized struggles for housing challenge Brazil’s exclusionary urbanization. Occupations of vacant buildings by social movements have been pressing municipalities to guarantee the right to the city. Climate change accentuates the risks associated with exclusionary urbanization, and responses to its impacts demand mitigation and adaptation measures that support transformations tackling inequalities and vulnerabilities. This paper highlights the dimensions of inequality, as well as the role of social movements in setting an agenda on climate justice while reducing vulnerability and creating housing alternatives in vacant central buildings of São Paulo and Natal. To this end, we conducted a review of relevant literature along with participatory action-research on insurgent practices of housing social movements in both cities.