Giant Adrenal Myelolipoma: Report of a Case

Akamatsu, Hiroki; Koseki, Masato; Nakaba, Hiroyuki; Sunada, Shoji; Itō, Akira; Teramoto, Seiichi; Miyata, Masahiko

doi:10.1007/s00595-003-2682-4

Cited by 55 publications

(51 citation statements)

References 6 publications

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“…Also, the case reported by Akamatsu and coworkers in the left adrenal gland of a 51-year-old man weighed 6000 g (310 mm), which is the heaviest adrenal myelolipoma reported (Akamatsu et al 2004).…”

Section: :3mentioning

confidence: 94%

Lipomatous tumours in adrenal gland: WHO updates and clinical implications

Lam¹

2017

Endocrine-Related Cancer

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Adrenal lipomatous tumour is a group of adrenal tumours with a significant component of adipose tissue. According to the current World Health Organization (WHO) classification of tumours of endocrine organs, adrenal myelolipoma is the only entity amongst the group of tumours being described. In the literature, other more recently documented adrenal lipomatous tumours included 24 lipomas, 32 teratomas and 16 angiomyolipomas. Rare fatty tumours of the adrenal gland comprised liposarcoma, hibernoma, adrenocortical tumours with fat component and rare adrenal tumours with fat component. Myelolipoma comprises approximately 3% of primary adrenal tumour. It is noted more commonly in females and in the right adrenal gland. Approximately 40 bilateral myelolipomas were reported. The tumour is most frequently recorded in patients between fifth and seventh decades of life. Adrenal lipomas are often seen in males and in the right adrenal gland. They were commonly noted in patients in the sixth decade of life. The diagnosis could only be possible on examination of the surgically removed specimen. Adrenal teratomas were more common in females and with a bimodal age distribution. Slightly over 60% of the patients with adrenal teratoma are symptomatic. Adrenal angiomyolipomas were often symptomatic, more common in females and in the fifth decades of life. To conclude, adrenal lipomatous tumour is uncommon. They are often benign and non-functional. It is important to recognize the features of this group of lipomatous tumours in the adrenal gland as they are being detected on increasing incidence as a result of the wide-spread use of modern imaging modalities.

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Section: :3mentioning

confidence: 94%

Lipomatous tumours in adrenal gland: WHO updates and clinical implications

Lam¹

2017

Endocrine-Related Cancer

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“…These lesions are thus occasionally detected as an incidental finding during laparotomy or necropsy. A few cases of giant myelolipomas over 10 centimeters in diameter have been reported in humans [1,3], causing clinical symptoms including abdominal pain, nausea and vomiting and thus differing from the more typical asymptomatic cases of myelolipoma. In the case of the present dog, myelolipoma on the greater omentum formed a large mass over 4 cm in diameter.…”

mentioning

confidence: 99%

Multicentric Myelolipoma in a Dog

Kamiie

Fueki

Amagai

et al. 2009

The Journal of Veterinary Medical Science

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ABSTRACT. We report herein a case of multicentric myelolipoma in an 11-year-old beagle dog that presented with vomiting. Laparotomy demonstrated the presence of a large mass adherent to the greater omentum and multiple small white maculae in the spleen. Cytological and histological examinations revealed that the mass and maculae comprised mature adipocytes and hematopoietic elements including granulocytic, erythrocytic and megakaryocytic series in several phases of maturation and macrophages containing hemosiderin deposits, resembling bone marrow. Multicentric myelolipoma was diagnosed. This is first report of multicentric myelolipoma in a dog.

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“…Largest tumor was described by Akamatsu and colleagues (diameter 31 cm, weight 6 kg). 15 In present series the mean size of the tumor was 14 cm and largest described was 26 cm. Majority (93%) were symptomatic ( Figure 1).…”

Section: Discussionmentioning

confidence: 50%