Giant Cell Tumor Originating from the Anterior Arc of the Rib

Abstract

We report a case of giant cell tumor originating from the anterior arc of the rib. The tumor and the surrounding chest wall were completely resected, and the chest wall defect was covered with Marlex mesh. Giant cell tumor of the bone usually originates from the epiphysis of long bones. Even when the tumor occur in ribs, it usually occur in the posterior aspect. However, giant cell tumor should be included in the differential diagnosis of a tumor originating from the anterior arc of the ribs.

Giant Cell Tumour of the Anterior rib arc Masquerading as a Primary Breast Lump

“…A rib is an uncommon site for origin of a GCT with a reported incidence of less than one percent. Even in the cases involving the rib, most were located in the posterior arc [1,2], anterior arc involvement was noted in our patient.…”

“…It is a benign but locally aggressive neoplasm, classically seen as a purely lytic lesion of the epiphyseal or metaphyseal-epiphyseal region of long tubular bones extending to the articular surface. Around 60 % of the tumours arise around the knee joint, isolated cases have been reported in the scapula, sternum, patella, vertebra, skull, and talus [1]. A rib is an uncommon site for origin of a GCT with a reported incidence of less than one percent.…”

Anterior chest wall giant cell tumor

“…Even in cases involving the ribs, most of the tumors were located in the posterior arc of the ribs, the head (epiphysis), and the tubercle of the ribs. [1][2][3]7 Because of its rarity, GCT arising from the rib is diffi cult to diagnose, especially when the tumor is located in the anterior arc. In our case, the initial impression included plasmacytoma, lymphoma, chondrosarcoma, metastatic tumor, and small round cell tumor.…”

“…Involvement of the rib is seen in fewer than 1% of all cases of GCT. [1][2][3][4][5] Even when the tumor occurs in a rib, it is usually in the posterior aspect such as the epiphysis of the head and tubercle of the rib, although it may also have an uncommon presentation as an anterior chest wall tumor. 1,2,6,7 We report a case of GCT originating from the anterior arc of the rib.…”

Giant cell tumor of patella

“…Rare multicentric forms have been reported [1][2][3] . In this article, we report a case of GCT originating from the right patella which was diagnosed on •ne needle aspiration cytology (FNAC).…”