Giant‐cell tumours of soft tissues

Salm, R.; Sissons, H. A.

doi:10.1002/path.1711070106

Cited by 161 publications

(130 citation statements)

References 26 publications

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“…Soft tissue GCT, first described by Salm and Sissons (14) in 1972, is a rare neoplasm located in both superficial and deep soft tissue. It commonly involves the upper and lower extremities.…”

Section: Discussionmentioning

confidence: 99%

Tumors of the Foot and Ankle: A Single-institution Experience

Azevedo

Casanova

Guerra

et al. 2013

The Journal of Foot and Ankle Surgery

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Level of Clinical Evidence: 4Keywords: bone giant cell tumor neoplasm sarcoma soft tissue surgery a b s t r a c t Tumors of the foot and ankle are rare, and the particular clinicopathologic features, therapeutic approach, and outcomes in this setting are not well established. From January 2000 to December 2010, 72 patients with primary musculoskeletal tumors of the foot and ankle, both benign and malignant, were treated at a single institution. Of the 72 patients, 56% were female. The median age was 52 years. Of the 72 tumors, 62 (86.11%) were located in the foot and 10 were located in the ankle; 63 (87.5%) were soft tissue tumors and 9 (12.5%) were bone tumors. Overall, 56 (78%) were benign tumors and 16 (22%) were malignant tumors. The most frequent soft tissue and bone diagnosis was giant cell tumor. The median follow-up period was 49 months. The vast majority of the tumors were located in the foot. Benign tumors were dominant, outnumbering malignant tumors by more than 3 to 1. The diversity of the histologic benign types was evident, with giant cell tumor, angiomyoma, and lipoma the most frequent. Regarding the malignant tumors, a clear male predominance was present, the median age was 45 years, and the most frequent tumor was synoviosarcoma. The 9-year overall and disease-free survival rate was 65% and 40%, respectively.

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Section: Discussionmentioning

confidence: 99%

Tumors of the Foot and Ankle: A Single-institution Experience

Azevedo

Casanova

Guerra

et al. 2013

The Journal of Foot and Ankle Surgery

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“…Introduction G iant cell tumor of soft tissue (GCT-ST) is a relatively rare entity, and is clinically and histomorphologically indistinguishable from its counterpart in bone [1,2]. It affects adults of both sexes.…”

Section: Original Articlementioning

confidence: 99%

“…Although GCT-ST is predominantly a benign condition, its capacity to occasionally recur or evolve into a malignant lesion is well recognized. If surgically treated with wide excision, it is expected to have a benign clinical course [1,2].…”

Section: Original Articlementioning

confidence: 99%

Study of 7 Cases of Giant Cell Tumor of Soft Tissue

Chand

Bhardwaj²,

Rappai³

2006

Medical Journal Armed Forces India

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“…Primary giant cell tumor of the soft tissue (PGCT-ST) was first defined by Salm and Sissons as a tumoral lesion histologically identical to the giant cell tumor of bone [1]. The authors has noticed on that even though having some local recurrences on two patients, these tumors was clinically benign without metastases.…”

Section: Introductionmentioning

confidence: 99%

“…These lesions show correspondence to benign edge of the spectrum of PGCT-ST [3]. Salm and Sissons [1] had impressed at the base of the relatively absence or minimality of solid component and uniformly cystic nature of the tumor. Also O'Connell et al [3] thinks the same with Salm and Sissons about this issue.…”

mentioning

confidence: 99%