Giant Congenital Melonocytic Nevi of Face-Primary Excision with Reconstruction Using Self-Filling Osmotic Expanders

Venugopal, P

doi:10.1007/s12262-015-1246-3

Cited by 2 publications

(3 citation statements)

References 19 publications

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“…After the removal of 210 duplicates and 160 irrelevant studies, 167 full-text articles were assessed for eligibility, of which 23 met inclusion criteria. The included studies were then cross-referenced and a further 11 studies met the inclusion criteria, totaling 34 included studies for thematic analysis 9–42 . Two additional identified studies did not explicitly report any outcome, aside from complications, and did not include any aesthetic-related information and were excluded 43,44 .…”

Section: Resultsmentioning

confidence: 99%

“…Within the included studies, 53% reported on a conservative treatment modality, 9,[13][14][15]18,19,[22][23][24][25][26]30,32,33,35,39,41,42 44% reported on surgical excision of FCMN, [10][11][12]16,17,20,21,[27][28][29]31,34,36,38,40 and 3% used a combined, surgical and conservative treatments. 37 Following surgical excision, 27% of studies reported reconstruction using a flap, and 21% used a full-thickness skin graft (FTSG).…”

Section: Treatment Patternsmentioning

confidence: 99%

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Surgery or Not? A Systematic Review of Facial Congenital Melanocytic Nevi Treatment Patterns and Outcomes

Ibelli,

Bauer,

Kleinman

et al. 2023

Ann Plast Surg

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Background Treatment management for congenital melanocytic nevi (CMN) on the face (FCMN) is highly variable and requires a thorough assessment of multiple factors. To date, a systematic review of FCMN treatment is lacking. The purpose of the present study was to elucidate the frequency, variety, and outcomes of treatment modalities for FCMN with different levels of complexity. Methods A comprehensive review of Pubmed, Embase, and Google Scholar databases from 1950 to 2022 was conducted using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Articles reporting on FCMN treatment approaches, outcomes, and associated complications were screened and data were extracted according to inclusion criteria. Data were tabulated for thematic analysis of FCMN treatment types, anatomic locations, outcomes, and complications. Results Of the 561 studies retrieved, 34 met inclusion criteria including 19 surgical treatments, 14 nonsurgical treatments, and one combined surgical and nonsurgical treatment study, totaling 356 patients. The majority of treated FCMN were small-to-medium-sized (56%). Facial CMN treated conservatively were mostly located on the cheek (27%) and/or perinasal region (21%), whereas FCMN treated with surgery were primarily located in the periorbital region (44%) and/or the cheek (17%). Across all treatment cohorts, 22% of patients experienced at least one complication, with 12% of complications experienced by patients treated by surgery. Conclusions There is a greater need for standardized FCMN nomenclature that encompasses nevi pattern, dimensions, anatomical coverage, and quantitative measurements of treatment outcome. Future studies should focus on identifying anatomic locations of FCMN that are more prone to complications and determine which treatment approach optimizes outcomes.

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Section: Resultsmentioning

confidence: 99%

Section: Treatment Patternsmentioning

confidence: 99%

Surgery or Not? A Systematic Review of Facial Congenital Melanocytic Nevi Treatment Patterns and Outcomes

Ibelli,

Bauer,

Kleinman

et al. 2023

Ann Plast Surg

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“…Having once decided to perform surgery, there are many options described: stage excision, skin grafting, tissue expansion, tangential shaving, derm-abrasion and pedicled, or free flaps. [ 4 , 5 ] All above methods, however, either need multistage surgery or cause new damage to the normal skin. What's more, for those GCMN which we define as involving over 10% of the total body surface area (TBSA), it is impractical to reconstruct the defects by autologous skin graft or tissue expansion following complete resection, as it is hard for both healthcare providers and patients to accept such extensive new scar formation at the normal donor sites.…”

Section: Introductionmentioning

confidence: 99%

An alternative strategy treated giant congenital melanocytic nevi with epidermis and superficial dermis of the lesions

Wang²,

Luo³

et al. 2018

Medicine

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Giant congenital melanocytic nevi (GCMN) are defined as rare pigmented lesions that are believed to form between weeks 9 and 20 of gestation. It is difficult to reconstruct large defects after the removal of the lesions and it has posed a great challenge to the plastic surgeon and dermatologist.Given all those difficulty reconstructing the defects, we try to explore an alternative way to resurfacing the defect after removal of GCMN.Patients with GCMN received single-stage excision. Following the subcutaneous tissue and deep dermis were discarded, epidermis and superficial dermis were harvested as graft substitutes to reconstruct the defects in situ.All of the grafted tissue survived well and skin color in the surgical area gradually became lighter. During the periodicity of follow-up, neither hypertrophic scars nor recurrence were observed. Furthermore, histopathology examination demonstrated that there are no distinct melanocytes gathered in the postoperation lesions.For those GCMN which is difficult to reconstruct with traditional methods, resection of the lesion followed by reconstruction with epidermis skin and superficial dermis from the lesions in situ may be a feasible and alternative therapy method.

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Giant Congenital Melonocytic Nevi of Face-Primary Excision with Reconstruction Using Self-Filling Osmotic Expanders

Cited by 2 publications

References 19 publications

Surgery or Not? A Systematic Review of Facial Congenital Melanocytic Nevi Treatment Patterns and Outcomes

Surgery or Not? A Systematic Review of Facial Congenital Melanocytic Nevi Treatment Patterns and Outcomes

An alternative strategy treated giant congenital melanocytic nevi with epidermis and superficial dermis of the lesions

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