Giant Leiomyoma of the Small Intestine With Free Perforation into the Peritoneal Cavity

Spontaneous perforation of jejunal gastrintestinal stromal tumour (gist). Case report and review of literature

“…Seventy percent are symptomatic at presentation, 20% are asymptomatic and 10% are detected at autopsy [5,6]. Common presentations include abdominal pain, palpable mass, gastro intestinal bleeding, fever, anorexia, weight loss and anaemia [7].…”

“…Clinical diagnosis of GIST is based on index of suspicion [6,7]. Specific diagnostic signs and symptoms are absent.…”

“…The decisive diagnosis rests on the pathological and immunohistological tests [2,5-10]. Histopathologically GISTs are composed of spindle (70%), epithelioid and round cell or an admixture [6,8]. Similarities with histological picture of gastrointestinal leiomyosarcoma, leiomyoblastoma and poorly differentiated carcinomas may cause diagnostic dielemma, Immuno-histochemical assays for CD117 antigen (KIT) is the mainstay for diagnosis [9,10].…”

Emergency Atypical Resection for Perforated Gastric Gist

“…Perforation is extremely rare. There are 16 cases in medical literature of GIST tumors with this debut, all in jejunum [7], including a jejunal diverticulum [8]. No documented cases of gastric perforation until today, but there is an esophageal perforation [9].…”

Spontaneous perforation of jejunal gastrointestinal stromal tumour presenting with multiple intraperitoneal abscess cavities: a case report and review of literature

“…12 Local and regional lymph node involvement is infrequent in GIST. 14,15 GIST's presenting with perforation, attention needs to be paid, in view of possible recurrence of the tumor. Abundant peritoneal lavage should be performed with distilled water to reduce the risk of peritoneal tumour spillage.…”