Giant Molluscum Contagiosum: Does it Affect Truly Immunocompetent Individuals?

Matsuda, Marcelo Mitsuro; Bloch, Leila David; Arnone, Marcelo; Vasconcelos, Dewton de Moraes; Nico, Marcello Menta Simonsen

doi:10.1080/00015550410023536

Cited by 7 publications

(8 citation statements)

References 7 publications

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“…Matsuda et al reported an otherwise healthy young adult with giant MC along with disseminated typical MC. 18 A thorough evaluation in this case revealed an abnormality of memory T-cell function. The authors conclude that giant MC may be due to an unrecognized selective immune deficiency.…”

Section: Discussionmentioning

confidence: 77%

A case series of giant molluscum contagiosum in an immigrant African pediatric population

Lee

Witman

Mosser

et al. 2021

Pediatric Dermatology

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Giant molluscum contagiosum (MC) has a well-known association with human immunodeficiency virus and other immune deficiency states. Although rare, it can be seen in healthy immunocompetent children. We describe eight cases of giant MC in healthy, immunocompetent African immigrant children in the Columbus, Ohio area. This report describes the clinical characteristics, treatment, and course of giant MC in this patient population.

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Section: Discussionmentioning

confidence: 77%

A case series of giant molluscum contagiosum in an immigrant African pediatric population

Lee

Witman

Mosser

et al. 2021

Pediatric Dermatology

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“…Immunocompetent individuals with MC infections typically do not require specific medications as the lesions eventually disappear spontaneously. 1,5,11…”

Section: Discussionmentioning

confidence: 99%

Molluscum Contagiosum Masquerading: Diagnosing Giant Lesions in an Unfamiliar Territory

Yaprak Bayrak,

Oncel,

Atayev

et al. 2024

Pediatric Infectious Disease Journal

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Molluscum contagiosum virus commonly affects children, causing localized skin diseases. We present the case of an immunocompetent 8-month-old patient with multiple giant molluscum contagiosum lesions. Lesions had a cup-like shape and were characterized by eosinophilic inclusion bodies on the keratinocytes as well as inverted lobules of hyperplastic squamous epithelium. It is crucial to identify this clinical variation to avoid unnecessary severe treatments.

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“…These lesions are rare in healthy children or adults and may accompany altered immunity, such as atopic dermatitis, corticosteroid and immunosuppressive therapy, sarcoidosis, leukemias, Wiskott-Aldrich syndrome and acquired immune deficiency syndrome. Atypical lesions of molluscum contagiosum may occur often and reach large size with extensive distribution on unusual body parts [3,4,7]. …”

Section: Discussionmentioning

confidence: 99%

“…There are only a few case reports of giant molluscum contagiosum occurring in immunocompetent patients in the literature [2,7]. Most of these patients are children without immunodeficiency.…”

Section: Discussionmentioning

confidence: 99%

Isolated giant molluscum contagiosum mimicking epidermoid cyst

Uzunçakmak

Kuru

Zemherı

et al. 2016

Dermatol Pract Concept

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Molluscum contagiosum is a benign cutaneous viral infection which is caused by double- stranded DNA poxvirus. It affects mainly children and young adults and usually presents with single or multiple umblicated papules or nodules on face, arms, legs and anogenital regions. It may present in atypical size and clinical appearance in patients with altered or impaired immunity and rarely in immuncompetent patients. Herein we present an immuncompetent young adult patient with isolated giant molluscum contagiosum, which was mimicking epidermoid cyst clinically.

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Giant Molluscum Contagiosum: Does it Affect Truly Immunocompetent Individuals?

Cited by 7 publications

References 7 publications

A case series of giant molluscum contagiosum in an immigrant African pediatric population

A case series of giant molluscum contagiosum in an immigrant African pediatric population

Molluscum Contagiosum Masquerading: Diagnosing Giant Lesions in an Unfamiliar Territory

Isolated giant molluscum contagiosum mimicking epidermoid cyst

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