Giardiasis Following Gastric Surgery

Slonim, J. M.; Ireton, H. J. C.; Smallwood, R A

doi:10.1111/j.1445-5994.1976.tb03040.x

Cited by 11 publications

(1 citation statement)

References 8 publications

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“…Over 54% of patients with symptomatic giardiasis have reduced gastric acid secretion [107]. That this reduced secretion is a factor predisposing to rather than resulting from giardiasis is suggested by observations of florid giardial infections following gastric surgery [108,109] and by the fact that achlorhydric individuals have a higher incidence of giardiasis [108,110].…”

Section: Synergismmentioning

confidence: 99%

Giardiasis: Nutritional Implications

Solomons¹

1982

Clinical Infectious Diseases

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The debate about the pathogenicity of Giardia lamblia in man has ended, and the issues regarding the prevalence of clinical and subclinical infections and their nutritional impact have become the foremost considerations. Giardiasis can produce steatorrhea, maldigestion, and malabsorption of carbohydrates and of vitamins A and B 12 • The mechanisms of the absorptive dysfunction are not clear, but morphological abnormalities of the intestinal mucosa and/or bacterial overgrowth might playa role. Severe clinical giardiasis can cause "failure to thrive" in young children, but the impact, if any, of subclinical giardiasis on growth in general populations is not well defined. Proteinenergy malnutrition appears to predispose to giardial infection, perhaps because of the accompanying hypochlorhydria, immunosuppression, and altered gastrointestinal flora. The lack of a sensitive and noninvasive diagnostic test for human giardial infection limits the investigation of the nutritional correlates of giardiasis.

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