2010
DOI: 10.1098/rsta.2010.0153
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GIMI: the past, the present and the future

Abstract: In keeping with the theme of this year's e-Science All Hands Meeting-past, present and future-we consider the motivation for, the current status of, and the future directions for, the technologies developed within the GIMI (Generic Infrastructure for Medical Informatics) project. This analysis provides insights into how some key problems in data federation may be addressed. GIMI was funded by the UK's Technology Strategy Board with the intention of developing a service-oriented framework to facilitate the secu… Show more

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Cited by 7 publications
(3 citation statements)
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“…Complementing standalone tools that provide medical image and/or simulation analysis toolchains, such as SimBio [22], COPHIT [10], BloodSim [58], euHeart [73], IMPPACT [57], or, much earlier, RAPT, newer platforms exist to bring analysis to a distributed setting, in some cases adapting existing standalone frameworks [13,72]. The extension to a generic toolchain using scientific middleware is a challenge that has been impeded by closed extensions in proprietary tools [72], and evolutionary developments have moved closer to open, standardized protocols, incorporating web technologies for improved quality of service [21]. A more extensive overview of international computational projects in biomedicine is provided in [44] and [61].…”
Section: Introductionmentioning
confidence: 99%
“…Complementing standalone tools that provide medical image and/or simulation analysis toolchains, such as SimBio [22], COPHIT [10], BloodSim [58], euHeart [73], IMPPACT [57], or, much earlier, RAPT, newer platforms exist to bring analysis to a distributed setting, in some cases adapting existing standalone frameworks [13,72]. The extension to a generic toolchain using scientific middleware is a challenge that has been impeded by closed extensions in proprietary tools [72], and evolutionary developments have moved closer to open, standardized protocols, incorporating web technologies for improved quality of service [21]. A more extensive overview of international computational projects in biomedicine is provided in [44] and [61].…”
Section: Introductionmentioning
confidence: 99%
“…To provide more functions, more data tend to be exposed to users, and then the risk of compromising confidential information inevitably rises. Meanwhile, to better protect patients' personal and medical information, some functions have to be reduced from systems [4,5,6].…”
Section: Introductionmentioning
confidence: 99%
“…There are various work-arounds, for instance, Markov random field theory allows to work directly on the inverse matrix, i.e., the precision matrix, (Rue 2001;Simpson, Lindgren, and Rue 2011). Composite likelihood approaches simplify the likelihood function by additional assumptions, cf.…”
Section: Simulation and Inferencementioning
confidence: 99%