2021
DOI: 10.1016/j.semcancer.2019.08.009
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Ginger and its active compounds in cancer therapy: From folk uses to nano-therapeutic applications

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Cited by 116 publications
(79 citation statements)
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“…However, symptoms and evaluation methods varied among studies, with substandard general qualities, making it challenging to integrate outcomes. Investigations on the anticancer activity of ginger or its active constituents, especially shogaols and gingerol species, have been conducted in various types of cancer with different models [6,82]. However, there was no direct evaluation of the incidence or survival of patients in the four trials that evaluated ginger's effect on colorectal cancer.…”
Section: Discussionmentioning
confidence: 99%
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“…However, symptoms and evaluation methods varied among studies, with substandard general qualities, making it challenging to integrate outcomes. Investigations on the anticancer activity of ginger or its active constituents, especially shogaols and gingerol species, have been conducted in various types of cancer with different models [6,82]. However, there was no direct evaluation of the incidence or survival of patients in the four trials that evaluated ginger's effect on colorectal cancer.…”
Section: Discussionmentioning
confidence: 99%
“…More than approximately 100 compounds have reportedly been isolated from ginger [5]. Specifically, the major classes of ginger compounds are gingerol, shogaols, zingiberene, and zingerone, as well as other less common compounds, including terpenes, vitamins, and minerals [6]. Among them, gingerols are considered as the primary components, reported to possess several bioactivities [7].…”
Section: Introductionmentioning
confidence: 99%
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“…in silico studies. In order to determine the inhibitory impact of ginger phytochemicals on hFASN through in silico studies, various biologically active ginger compounds were selected from literatures [29][30][31][32] . Two domains of the enzyme were selected to perform docking simulation study; the ketosynthase (KS) and thioesterase (TE) domains.…”
Section: Methodsmentioning
confidence: 99%
“…Jahe adalah tumbuhan aromatis dengan rimpang bercabang simpodial, batang semu dengan tinggi sekitar 1 m dan kaya akan flavonoid. 1 Secara umum jahe digunakan sebagai obat tradisional untuk mengobati mabuk perjalanan, mual, muntah, diare, batuk, nyeri otot, demam, migraine dan perdarahan. Namun dalam penelitian beberapa tahun terakhir, telah ditemukan bahwa jahe memiliki aktivitas biologik yang dapat digunakan sebagai antiulkus, antioksidan, dan antiinflamasi.…”
Section: Pendahuluanunclassified