Ginger in the Prevention of Nausea and Vomiting: A Review

Abstract

Nausea and vomiting are physiological processes experienced by every human being at some stage of their life. They are complex protective mechanisms and the symptoms are influenced by the emetogenic response and stimuli. However, when these symptoms recur frequently, they can significantly reduce the quality of life and can also be detrimental to health. The existing antiemetic agents are ineffective against certain stimuli, are expensive, and possess side effects. Herbal medicines have been shown to be effective antiemetics, and among the various plants studied, the rhizome of Zingiber officinale, commonly known as ginger, has been used as a broad-spectrum antiemetic in the various traditional systems of medicine for over 2000 years. Various preclinical and clinical studies have shown ginger to possess antiemetic effects against different emetogenic stimuli. However, conflicting reports especially in the prevention of chemotherapy-induced nausea and vomiting and motion sickness prevent us from drawing any firm conclusion. The current review for the first time summarizes the results. An attempt is also made to address the lacunae in these published studies and emphasize aspects that need further investigations for it to be of use in clinics in the future.

Ginger Protects the Liver against the Toxic Effects of Xenobiotic Compounds: Preclinical Observations

“…In addition to its culinary use, ginger also possess medicinal properties, and has been used since antiquity to treat ailments like cold, headaches, nausea, stomach upset, diarrhea, digestive, gastrointestinal disturbances, rheumatic complaints, diarrhea, nausea, asthma and parasitic infections, arthritis and muscular discomfort in the various alternative and folk systems of medicine in the world [1][2][3][4][5][6][7]. Phytochemical studies have shown that the unique culinary and medicinal properties of ginger are due …”

“…, β-phellandrene, curcumene, cineole, geranyl acetate, terphineol, terpenes, borneol, geraniol, limonene, β-elemene, zingiberol, linalool, α-zingiberene, β-sesquiphellandrene, β-bisabolene, zingiberenol and α-farmesene [1][2][3][4][5][6][7]. Scientific studies carried out in accordance to the principles of modern system of medicine have convincingly shown that ginger possesses numerous health benefits like antimicrobial, antiviral, gastroprotective, antidiabetic, anti-hypertensive, cardioprotective, anticancer, chemopreventive and immunomodulatory effects [1,4].…”

Visceral hypersensitivity and electromechanical dysfunction as therapeutic targets in pediatric functional dyspepsia

“…Complementary therapies such as ginger [189,190] , peppermint oil [191] , and iberogast [192] , may also have a role in the treatment of FD. Ginger enhances gastric emptying in healthy volunteers and adults with FD but had no impact on FD symptoms [193,194] .…”

GERMINAÇÃO E DESENVOLVIMENTO DE PLÂNTULAS DA ALFACE (Lactuca sativa L.) EM DIFERENTES EXTRATOS DE Zingiber officinale Roscoe

“…Usualmente, os fitoterápicos tradicionais são preparados a partir do rizoma da planta e empregados no tratamento de problemas gastrointestinais (USHA & KRISHNAPURA, 2010), agindo também como anti-inflamatório, diurético, expectorante e atuando na diminuição e controle de glicemia e colesterol (PALATTY et al, 2013). No Brasil, o conhecimento relacionado ao uso de plantas para o tratamento, prevenção de enfermidades e o seu modo de preparo é transmitido ao longo das gerações, sendo esta a principal forma de uso, mesmo com a crescente produção industrial de medicamentos e produtos fitoterápicos (OSHIRO et al, 2016).…”