2010
DOI: 10.2478/v10153-010-0017-y
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Gingival Disease and Secretory Immunoglobulin a In Non-Stimulated Saliva in Children

Abstract: SIgA is a factor characterizing the local specific immunity which depends on local antigenic stimuli (plaque biofilm), but it does not affects the gingival pathology directly. SIgA can be considered an important part of an integrated assessment of oral risk environments.

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Cited by 13 publications
(12 citation statements)
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“…Decreased IgA levels in saliva are associated with an increased degree of gingival inflammation [24]. The results of our study are aligned with those obtained by Shilpashree, who highlighted a decrease in IgA in cigarette smokers [1].…”
Section: Discussionsupporting
confidence: 91%
“…Decreased IgA levels in saliva are associated with an increased degree of gingival inflammation [24]. The results of our study are aligned with those obtained by Shilpashree, who highlighted a decrease in IgA in cigarette smokers [1].…”
Section: Discussionsupporting
confidence: 91%
“…Inflammatory and microbiological disease of the oral cavity can also be related to immunoglobulin concentration . A relationship was established among immunoglobulin levels, the periodontal disease (gingival index), and the Loe bacterial plaque index .…”
Section: Discussionmentioning
confidence: 99%
“…This latter observation taken together with the previous literature suggest several mechanisms by which low sIgA and high IgA might both relate to mortality; low sIgA might indicate impaired immunity with ageing, which in turn influences both infectious disease risk and cancer risk, whereas high serum IgA may indicate already underlying disease. Nevertheless, it should also be noted that in some instances, abnormally high sIgA levels indicate current acute oral infection [ 7 ], and inflammation [ 8 ].…”
Section: Resultsmentioning
confidence: 99%
“…However, the relationship between sIgA and health is complex and subject both to confounding and reverse causation. For example, in the case of oral health, lower levels of sIgA have been shown to be a risk marker for dental caries and decay [ 6 ] but high levels have been deemed an indicator of current oral infection [ 7 – 9 ].…”
Section: Introductionmentioning
confidence: 99%