Ginseng face cream and unexplained vaginal bleeding

Hopkins, Michael P.; Androff, Lynn; Benninghoff, Anne S.

doi:10.1016/0002-9378(88)90426-7

Cited by 95 publications

(38 citation statements)

References 2 publications

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“…The clinical scientific evidence for this risk is weak, consisting primarily of a handful of anecdotal reports of catastrophic bleeding in herbal users. [7][8][9][10][11][12][13][14][15][16][17][18][19][20][21] However, several herbal extracts have been identified experimentally to possess antiplatelet activity in vitro. 7,14,15,[22][23][24][25][26][27][28][29][30][31][32] The purpose of this investigation was to determine whether standard commercial preparations of commonly used herbal medicines have an effect on platelet function in vivo and, by extension, to provide clinical scientific evidence of their safety when used in the perioperative period.…”

mentioning

confidence: 99%

The Effect of Herbal Medicines on Platelet Function: An In Vivo Experiment and Review of the Literature

Beckert

Concannon

Henry

et al. 2007

Plastic and Reconstructive Surgery

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mentioning

confidence: 99%

The Effect of Herbal Medicines on Platelet Function: An In Vivo Experiment and Review of the Literature

Beckert

Concannon

Henry

et al. 2007

Plastic and Reconstructive Surgery

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“…77 In one case, postmenopausal bleeding was attributed to the estrogen-like effect of topical ginseng. 78 Thus, caution is needed when ginseng is taken concomitantly with anticoagulation and anti-inflammatory pharmaceuticals. In particular, concomitant use of ginseng with warfarin or aspirin should be avoided.…”

Section: Ginseng (Panax Ginseng Ginseng Panax Quinquefolius)mentioning

confidence: 99%

Bleeding Risks of Herbal, Homeopathic, and Dietary Supplements: A Hidden Nightmare for Plastic Surgeons?

Wong

Gabriel

Maxwell

et al. 2012

Aesthetic Surgery Journal

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The utilization of complementary and alternative medicine has increased tremendously in the last two decades. Herbal products, homeopathic medicines, and dietary supplements are extremely popular and are available without a prescription (which likely contributes to their popularity). Despite their "natural" characteristics, these remedies have the potential to cause bleeding in patients who undergo surgery. The high use of these supplements among cosmetic surgery patients, coupled with increasing reports of hematomas associated with herbal and homeopathic medicines, prompted the authors to conduct a comprehensive review focused on bleeding risks of such products in an effort to raise awareness among plastic surgeons. This review focuses on 19 herbs, three herbal formulas, two herbal teas, and several other supplements that can cause bleeding perioperatively and postoperatively. In addition to being aware of such adverse effects, plastic surgeons must adequately screen all patients and educate them on the possible dangers associated with these treatments.

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“…Ginseng has been associated with a few episodes of spontaneous bleeding, (22)(23)(24) but have also been associated with reports of subtherapeutic INR and thrombosis in patients previously stable on warfarin. (25,26) The effect of ginseng on warfarin has not been replicated in clinical trials.…”

Section: Asian Ginseng 人参 (Panax Ginseng)mentioning

confidence: 99%

Interaction between warfarin and Chinese herbal medicines

Chua¹,

Ang²,

Zhong³

et al. 2015

smedj

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In traditional Chinese medicine (TCM), the human body is divided into Yin and Yang. Diseases occur when the Yin and Yang balance is disrupted. Different herbs are used to restore this balance, achieving the goal of treatment. However, inherent difficulties in designing experimental trials have left much of TCM yet to be substantiated by science. Despite that, TCM not only remains a popular form of medical treatment among the Chinese, but is also gaining popularity in the West. This phenomenon has brought along with it increasing reports on herb-drug interactions, beckoning the attention of Western physicians, who will find it increasingly difficult to ignore the impact of TCM on Western therapies. This paper aims to facilitate the education of Western physicians on common Chinese herbs and raise awareness about potential interactions between these herbs and warfarin, a drug that is especially susceptible to herb-drug interactions due to its narrow therapeutic range.

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Ginseng face cream and unexplained vaginal bleeding

Cited by 95 publications

References 2 publications

The Effect of Herbal Medicines on Platelet Function: An In Vivo Experiment and Review of the Literature

The Effect of Herbal Medicines on Platelet Function: An In Vivo Experiment and Review of the Literature

Bleeding Risks of Herbal, Homeopathic, and Dietary Supplements: A Hidden Nightmare for Plastic Surgeons?

Interaction between warfarin and Chinese herbal medicines

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