Global burden of hearing impairment and ear disease

Graydon, Kelley; Waterworth, Christopher J.; Miller, Hilary M.; Gunasekera, Hasantha

doi:10.1017/s0022215118001275

Cited by 143 publications

(110 citation statements)

References 78 publications

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“…This inequitable distribution may be explained by the increased exposures to risk factors across the life course in LMICs, compared to high income countries [4]. For example, increased exposure to infectious diseases, unregulated use of ototoxic medications, and noise exposure in the workplace [5]. The WHO estimate that over a third of people with moderate or greater hearing loss are aged over 65 years [6].…”

Section: Introductionmentioning

confidence: 99%

Field-testing of a rapid survey method to assess the prevalence and causes of hearing loss in Gao’an, Jiangxi province, China

Bright

Shan²,

Xu³

et al. 2020

Arch Public Health

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Background: The Rapid Assessment of Hearing Loss (RAHL) survey protocol aims to measure the prevalence and causes of hearing loss in a low cost and rapid manner, to inform planning of ear and hearing services. This paper reports on the first field-test of the RAHL in Gao'an County, Jiangxi Province, China. This study aimed to 1) To report on the feasibility of RAHL; 2) report on the estimated prevalence and causes of hearing loss in Gao'an. Methods: A cross-sectional population-based survey was conducted in September-October 2018. Forty-seven clusters in Gao'an County were selected using probability-proportionate-to-size sampling. Within clusters, compact segment sampling was conducted to select 30 people aged 50+. A questionnaire was completed covering sociodemographics, hearing health, and risk factors. Automated pure-tone audiometry was completed for all participants, using smartphone-based audiometry (hearTest), at 0.5, 1, 2, 4 kHz (kHz). All participants had their ears examined by an Ear Nose and Throat (ENT) doctor, using otoscopy, and probable causes of hearing loss assigned. Prevalence estimates were age and sex standardised to the Jiangxi population. Feasibility of a cluster size of 30 was examined by assessing the response rate, and the proportion of clusters completed in 1 day. Results: 1344 of 1421 eligible participants completed the survey (94.6%). 100% of clusters were completed in 1 day. The survey was completed in 4.5 weeks. The prevalence of moderate or greater hearing loss (pure-tone average of 0.5, 1, 2, 4 kHz of > = 41dBHL in the better ear) was 16.3% (95% CI = 14.3, 18.5) and for any level of hearing loss (pure-tone average of > = 26dBHL in the better ear) the prevalence was 53.2% (95% CI = 49.2, 57.1). The majority of hearing loss was due to acquired sensorineural causes (91.7% left; 92.1% right). Overall 54.0% of the population aged 50+ (108,000 people) are in need of diagnostic audiology services, 3.4% were in need of wax removal (7000 people), and 4.8% were in need of surgical services (9500 people). Hearing aid coverage was 0.4%. Conclusion: The RAHL survey protocol is feasible, demonstrated through the number of people examined per day, and the high response rate. The survey was completed in a much shorter period than previous all-age surveys in China. Some remaining challenges included assignment of causes of probable sensorineural loss. The data obtained from this survey can be used to scale-up hearing services in Gao'an.

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Section: Introductionmentioning

confidence: 99%

Field-testing of a rapid survey method to assess the prevalence and causes of hearing loss in Gao’an, Jiangxi province, China

Bright

Shan²,

Xu³

et al. 2020

Arch Public Health

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“…Hearing thresholds at octave frequencies from 0.125 to 8 kHz were measured. Hearing impairment was defined as the pure-tone average of air-conduction hearing threshold greater than 40 decibels hearing level (dB HL) at four frequencies (0.5, 1, 2, and 4 kHz) in the better ear, according to the WHO definition [12,13]. No subjects demonstrated profound hearing loss, as verbal communication would not have been practical; however, the MMSE-J was administered by a clinical psychotherapist using a bullhorn in some cases.…”

Section: Hearing Assessmentmentioning

confidence: 99%

Development of the Reading Cognitive Test Kyoto (ReaCT Kyoto) for Early Detection of Cognitive Decline in Patients with Hearing Loss

Okano

Yamamoto

Kuzuya

et al. 2020

JAD

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Background: Early detection of cognitive decline allows timely intervention to delay progression of dementia. However, current cognitive evaluation tools often include items delivered via verbal forms of instruction, which can cause poor performance in patients with hearing loss. Objective: To develop and validate a cognitive screening battery, the Reading Cognitive Test Kyoto (ReaCT Kyoto), comprising test items given through non-verbal instruction. Methods: A cross-sectional and multi-center study was conducted in the three medical institutes. ReaCT Kyoto was designed to evaluate domains of "registration," "repetition," "delayed recall," "visuospatial recognition," "orientation in time and place," and "executive function." The Japanese version of the Mini-Mental State Examination Test (MMSE-J) and ReaCT Kyoto were applied by experienced psychotherapists. Concurrent validity was evaluated between the ReaCT Kyoto Test and MMSE-J and between the ReaCT Kyoto Test and physician-diagnosed dementia. Results: ReaCT Kyoto was validated in a sample of 115 participants. The mean age of subjects was 81.0 ± 6.4 years, and the sample comprised 53.0% females. The area under the receiver operating curves was 0.95 for detecting physician-diagnosed dementia. When classifying patients in accordance with presence or absence of hearing loss, the AUCs were 0.93 and 0.97 for those with and without hearing loss, respectively. With a cutoff score of < 29 points for suspected dementia, ReaCT Kyoto correctly classified 90.4% of the subjects as belonging to the group with or without physician-diagnosed dementia. Conclusion: ReaCT Kyoto provides an appropriate solution for detection of cognitive impairment in persons with or without hearing loss.

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“…According to the most recent World Health Organization (WHO) estimates [4], over six percent of the world's population, representing approximately 460 million individuals, are currently living with a disabling HI, of which 93% are adults and mostly males (242 million males vs 190 million females). The financial burden associated with HI, which includes costs for healthcare, education, social support, and loss of productivity [5], is estimated to be 750 billion US dollars annually [6]. Even though 60% of HI cases can be prevented [5], the number of cases is expected to significantly increase to over 900 million in 2050 [4] with huge negative economic implications, unless action is taken.…”

Section: Introductionmentioning

confidence: 99%

“…The financial burden associated with HI, which includes costs for healthcare, education, social support, and loss of productivity [5], is estimated to be 750 billion US dollars annually [6]. Even though 60% of HI cases can be prevented [5], the number of cases is expected to significantly increase to over 900 million in 2050 [4] with huge negative economic implications, unless action is taken. As a matter of urgency, there is a need to strengthen collaborative HI research efforts aimed at curbing the projected increased burden of HI globally.…”

Section: Introductionmentioning

confidence: 99%

“…In the biomedical research context, several human disease-related ontologies have been introduced, including the Human Disease Ontology (DO), which consistently defines various concepts encountered in disease domains [13], the Mondo Disease Ontology, which provides a merged and comprehensive cross-species disease ontology (https://monarch-initiative.github.io/mondo/), and the Human Phenotype Ontology (HPO), providing controlled vocabularies of abnormal phenotypes encountered in human disease [14,15]. However, as previously argued in support of developing the Sickle Cell Disease Ontology (SCDO) [5], none of the existing ontologies comprehensively captures related concepts specific to HI due to the complex nature of HI etiologies and phenotypes.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

The Hearing Impairment Ontology: A Tool for Unifying Hearing Impairment Knowledge to Enhance Collaborative Research

Hotchkiss

Manyisa

Adadey

et al. 2019

Genes

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Hearing impairment (HI) is a common sensory disorder that is defined as the partial or complete inability to detect sound in one or both ears. This diverse pathology is associated with a myriad of phenotypic expressions and can be non-syndromic or syndromic. HI can be caused by various genetic, environmental, and/or unknown factors. Some ontologies capture some HI forms, phenotypes, and syndromes, but there is no comprehensive knowledge portal which includes aspects specific to the HI disease state. This hampers inter-study comparability, integration, and interoperability within and across disciplines. This work describes the HI Ontology (HIO) that was developed based on the Sickle Cell Disease Ontology (SCDO) model. This is a collaboratively developed resource built around the 'Hearing Impairment' concept by a group of experts in different aspects of HI and ontologies. HIO is the first comprehensive, standardized, hierarchical, and logical representation of existing HI knowledge. HIO allows researchers and clinicians alike to readily access standardized HI-related knowledge in a single location and promotes collaborations and HI information sharing, including epidemiological, socio-environmental, biomedical, genetic, and phenotypic information. Furthermore, this ontology illustrates the adaptability of the SCDO framework for use in developing a disease-specific ontology.

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Global burden of hearing impairment and ear disease

Abstract: This review aimed to present some of the leading causes of ear disease and hearing loss globally, and to identify their impact at both an individual and societal level.

Cited by 143 publications

References 78 publications

Field-testing of a rapid survey method to assess the prevalence and causes of hearing loss in Gao’an, Jiangxi province, China

Field-testing of a rapid survey method to assess the prevalence and causes of hearing loss in Gao’an, Jiangxi province, China

Development of the Reading Cognitive Test Kyoto (ReaCT Kyoto) for Early Detection of Cognitive Decline in Patients with Hearing Loss

The Hearing Impairment Ontology: A Tool for Unifying Hearing Impairment Knowledge to Enhance Collaborative Research

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