Global Left Ventricular Systolic Function Assessment

Madron, Éric de

doi:10.1016/b978-0-323-31650-7.00007-7

Cited by 9 publications

(20 citation statements)

References 46 publications

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“…In this study, EF and FS did not show a statistically significant decline throughout the experiment in comparison to the reference values (39.63 ± 6.26 and 70.9 ± 6.0), respectively [35], and could not exactly detect the deterioration in cardiac contractility as previously reported [19]. However, other studies in dogs reported a significant reduction in FS with a similar dose of DXR [31,36,37].…”

Section: Discussioncontrasting

confidence: 58%

The Utility of Intraventricular Pressure Gradient for Early Detection of Chemotherapy-Induced Subclinical Cardiac Dysfunction in Dogs

Matsuura

Shiraishi

Mandour

et al. 2021

Animals

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Early detection of doxorubicin (DXR)-induced cardiomyopathy (DXR-ICM) is crucial to improve cancer patient outcomes and survival. In recent years, the intraventricular pressure gradient (IVPG) has been a breakthrough as a sensitive index to assess cardiac function. This study aimed to evaluate the usefulness of IVPG for the early detection of chemotherapy-related cardiac dysfunction. For this purpose, six dogs underwent conventional, speckle tracking, and color M-mode echocardiography concomitantly with pressure-and-volume analysis by conductance catheter. The cardiac function measurements were assessed before DXR administration (baseline, Pre), at the end of treatment protocol (Post), and at 1.5 years follow-up (Post2). The result showed a significant reduction in the left ventricular end-systolic pressure-volume (Emax: 4.4 ± 0.7, 6.1 ± 1.6 vs. 8.4 ± 0.8 mmHg/mL), total-IVPG (0.59 ± 0.12, 0.62 ± 0.15 vs. 0.86 ± 0.12 mmHg), and mid-IVPG (0.28 ± 0.12, 0.31 ± 0.11 vs. 0.48 ± 0.08 mmHg), respectively in Post2 and Post compared with the baseline (p < 0.05). Mid-to-apical IVPG was also reduced in Post2 compared with the baseline (0.29 ± 0.13 vs. 0.51 ± 0.11). Meanwhile, the fraction shortening, ejection fraction, and longitudinal strain revealed no change between groups. Total and mid-IVPG were significantly correlated with Emax (R = 0.49; p < 0.05, both) but only mid-IVPG was a predictor for Emax (R2 = 0.238, p = 0.040). In conclusion, this study revealed that impairment of contractility was the initial changes observed with DXR-ICM in dogs and only IVPG could noninvasively detect subclinical alterations in cardiac function. Color M-mode echocardiography-derived IVPG could be a potential marker for the early detection of doxorubicin cardiomyopathy.

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Section: Discussioncontrasting

confidence: 58%

The Utility of Intraventricular Pressure Gradient for Early Detection of Chemotherapy-Induced Subclinical Cardiac Dysfunction in Dogs

Matsuura

Shiraishi

Mandour

et al. 2021

Animals

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“…36,38,39 Peak systolic velocities will be recorded from the septal and lateral mitral annular sites as current guidelines by using tissue Doppler imaging. 35,38,40 Left ventricle chamber measurements and indexes (secondary outcome). Left ventricular mass and relative wall thicknesses will be calculated based on M-mode echocardiographic measurements according to current recommendations.…”

Section: F I G U R E  Incremental Exercise Test (Ietmentioning

confidence: 99%

Efficacy of high‐intensity interval training compared with moderate‐intensity continuous training on maximal aerobic potency in dogs: Trial protocol for a randomised controlled clinical study

Arias

Carvajal

et al. 2021

Veterinary Record Open

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“…The cat was initiated the following medications: . With the addition of taurine to commercial foods, the incidence of the disease decreased in cats (6,15). Nevertheless cats with DCM are encountered although they are fed with a balanced diet.…”

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confidence: 99%

“…It is difficult to distinguish between these two situations. Greet et al 12 Gallop sounds and systolic murmur can also accompany to DCM phenotype in cats (6,15).…”

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confidence: 99%

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Non-taurine responsive dilated cardiomyopathy in 2 cats

Sevim

Çolakoğlu

2021

Ankara Üniversitesi Veteriner Fakültesi Dergisi

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Feline dilated cardiomyopathy (DCM) is a rare disease characterized by myocardial failure and systolic dysfunction. Taurine deficiency is the most important cause of DCM phenotype in cats. A 2 year-old Scottish fold and a 8 month-old domestic shorthair cat referred to hospital with anorexia, weakness and increased respiratory effort. Based on electrocardiographic, radiographic and echocardiographic findings, the diagnosis of dilated cardiomyopathy was done in both the cases. The cases were managed with pimobendan, furosemide, acetylsalicylic acid and taurine. The cats were more active and clinically healthy during 15 days follow-up. No remarkable changes were observed in follow up echocardiographies. The cases presented here reflect clinical signs, cardiological examination findings, diagnosis and management of idiopathic dilated cardiomyopathy in 2 cats.

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Global Left Ventricular Systolic Function Assessment

Cited by 9 publications

References 46 publications

The Utility of Intraventricular Pressure Gradient for Early Detection of Chemotherapy-Induced Subclinical Cardiac Dysfunction in Dogs

The Utility of Intraventricular Pressure Gradient for Early Detection of Chemotherapy-Induced Subclinical Cardiac Dysfunction in Dogs

Efficacy of high‐intensity interval training compared with moderate‐intensity continuous training on maximal aerobic potency in dogs: Trial protocol for a randomised controlled clinical study

Non-taurine responsive dilated cardiomyopathy in 2 cats

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