Global Mortality Burden of Cirrhosis and Liver Cancer Attributable to Injection Drug Use, 1990–2016: An Age-Period-Cohort and Spatial Autocorrelation Analysis

Yang, Jing; Zhang, Yunquan; Luo, Lisha; Meng, Runtang; Yu, Chuanhua

doi:10.3390/ijerph15010170

Cited by 15 publications

(14 citation statements)

References 85 publications

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“…Period effect reflects the immediate impact of social factors on the incidence of diseases. 29 In this study, the period effect decreased after 2005 compared with 2000 to 2004, which may relate to one or more achievements in the field of public health in China. In 1989, China launched the “Chinese Dietary Guideline”, and launched the revision version in 1997, 2007, and 2016, separately.…”

Section: Discussionmentioning

confidence: 66%

Temporal Trend of Urolithiasis Incidence in China: An Age–Period–Cohort Analysis

Huang

Fan

et al. 2021

IJGM

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Purpose Urolithiasis is one of the commonest disease of the urinary system. This study aimed to assess the long-term urolithiasis incidence trends in China between 1990 and 2019. Patients and Methods The incidence data of urolithiasis were extracted from Global Burden of Disease Study 2019, and an age–period–cohort framework was used to estimate the age, period, and cohort effects. Results We found that the net drift was −2.72% (95% CI: −2.84% to −2.60%) per year for men and −2.14% (95% CI: −2.24% to −2.05%) per year for women, and except men in age group 0–4, the local drift values were below 0 in all age groups (P<0.05 for all) in both sexes during the period of 1990 to 2019. In the same birth cohort, the risk of incidence from urolithiasis rose first and then decreased with age for both sexes after controlling for period deviations, and in addition, after 20 years old, the risk of incidence of urolithiasis in men was higher than that in women (significantly with P<0.05). In general, the estimated period and cohort relative risks were found in similar downward patterns for both sexes. Conclusion In the past 30 years, the age-standard incidence of urolithiasis in both sex of Chinese people has decreased, but the crude incidence of urolithiasis in Chinese women has increased. Considering the aging of population structure in China, the overall number of female urolithiasis patients may increase, contributes to higher crude incidence rate. The problem of urolithiasis in Chinese women needs to be paid more attention.

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Section: Discussionmentioning

confidence: 66%

Temporal Trend of Urolithiasis Incidence in China: An Age–Period–Cohort Analysis

Huang

Fan

et al. 2021

IJGM

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“…The cohort effect reflects changes in disease risk in a particular birth cohort. 33 In the present study, the birth cohort effect showed that both males and females born more recently had lower risks of UTI. This may be related to changes in lifestyles, more-sanitary conditions, and improvements in health habits.…”

supporting

confidence: 50%

“…32 The period effect reflects the immediate impact of social factors on the incidence of disease. 33 The present study found that the risk of UTI in both males and females decreased after 2005 compared with 2000 to 2004. The reduced risk of male UTI may be related to greater attention being paid to male reproductive health in China in recent years.…”

supporting

confidence: 45%

Trends in Incidence of Urinary Tract Infection in Mainland China from 1990 to 2019

Yuan¹,

Shi²,

Li³

et al. 2021

IJGM

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Purpose: Urinary tract infection (UTI) is the second-most-common type of infection in China. This study aimed to determine the long-term trends in the incidence of UTI in Mainland China between 1990 and 2019. Materials and Methods: Data were extracted from the Global Burden of Disease Study 2019 and were analyzed with the age-period-cohort framework. Results: The net drift in the incidence of UTI was -0.37% (95% CI: -0.40%, -0.35%) in males and -0.25% (95% CI: -0.29%, -0.20%) in females. For males, the local drift was lower than 0 (P<0.05) among those younger than 90 years. For females, the local drift was lower than 0 (P<0.05) among those younger than 60 years and higher than 0 (P<0.05) in those aged 65-79 years. In the same birth cohort, the incidence of UTI was higher in females than in males in all age groups (P<0.05). The period relative risk (RR) showed a decreasing pattern after 2005 in both sexes. The cohort RR showed a downward trend of the birth cohort after 1905 for males and 1960 for females. Conclusion:The incidence has increased significantly among older females over the past 30 years. It is necessary to develop a comprehensive intervention plan for reproductive health services covering females and males of all ages.

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“…The main causes of liver fibrosis include chronic hepatitis C infection, abusing alcohol, and steatohepatitis . Advanced liver fibrosis can progress to cirrhosis over time, and cirrhosis may cause serious complications, such as hepatocellular carcinoma, liver failure, and portal hypertension . Cirrhosis is one of the leading causes of death in China and worldwide; thus, it is urgently needed for a better understanding of the molecular mechanism of the liver fibrosis progression.…”

Section: Introductionmentioning

confidence: 99%

Icariin‐induced miR‐875‐5p attenuates epithelial‐mesenchymal transition by targeting hedgehog signaling in liver fibrosis

Zhao

2019

J of Gastro and Hepatol

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Background Hepatic fibrosis is the final endpoint for most chronic liver diseases and remains a significant public health problem worldwide. Icariin, a naturally occurring flavonol glucoside, has been reported to exhibit protective effects on liver injury and alleviate liver fibrosis. However, the underlying detail molecular mechanism is not fully revealed. Methods Mouse primary hepatic stellate cells (HSCs) and carbon tetrachloride (CCL4)‐induced liver fibrosis model in mice were used as in vitro and in vivo models in this study. The expression levels of miR‐875‐5p were detected by quantitative reverse transcription‐PCR. The validation of the direct target of miR‐875‐5p was through dual‐luciferase reporter assay and western blotting assay. The cell proliferation and cell mobility were determined using MTT assay and Transwell migration assay, respectively. Results We found that icariin inhibited epithelial–mesenchymal transition and collagen protein section of HSCs. Icariin exerted hepatoprotective effects on mice model of CCL4‐induced liver fibrosis. Our further results revealed that miR‐875‐5p was downregulated in human cirrhosis tissues and activated murine HSCs. Icariin induced miR‐875‐5p upregulation and subsequently decreased glioma‐associated oncogene homolog 1 (GLI1) expression through direct binding to the three prime untranslated region of GLI1 mRNA. Conclusion Our study highlighted the potential therapeutic application of icariin for liver fibrosis management.

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Global Mortality Burden of Cirrhosis and Liver Cancer Attributable to Injection Drug Use, 1990–2016: An Age-Period-Cohort and Spatial Autocorrelation Analysis

Cited by 15 publications

References 85 publications

Temporal Trend of Urolithiasis Incidence in China: An Age–Period–Cohort Analysis

Temporal Trend of Urolithiasis Incidence in China: An Age–Period–Cohort Analysis

Trends in Incidence of Urinary Tract Infection in Mainland China from 1990 to 2019

Icariin‐induced miR‐875‐5p attenuates epithelial‐mesenchymal transition by targeting hedgehog signaling in liver fibrosis

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