Global progress in prevention of cardiovascular disease

Mendis, Shanthi

doi:10.21037/cdt.2017.03.06

Cited by 148 publications

(147 citation statements)

References 17 publications

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“…Among these, the cardiovascular system has received prominent attention due to the high death rate attributed to heart related diseases. In fact, the World Health Organization (WHO) has labeled cardiovascular diseases as the number one cause of death globally (Mendis, Puska & Norrving, 2011). Hence, cardiac aging has been an important area for research and clinical studies, and understanding heart rate patterns is an essential step in this study.…”

Section: Introductionmentioning

confidence: 99%

Aging and cardiovascular complexity: effect of the length of RR tachograms

Balasubramanian

Nagaraj

2016

PeerJ

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As we age, our hearts undergo changes that result in a reduction in complexity of physiological interactions between different control mechanisms. This results in a potential risk of cardiovascular diseases which are the number one cause of death globally. Since cardiac signals are nonstationary and nonlinear in nature, complexity measures are better suited to handle such data. In this study, three complexity measures are used, namely Lempel–Ziv complexity (LZ), Sample Entropy (SampEn) and Effort-To-Compress (ETC). We determined the minimum length of RR tachogram required for characterizing complexity of healthy young and healthy old hearts. All the three measures indicated significantly lower complexity values for older subjects than younger ones. However, the minimum length of heart-beat interval data needed differs for the three measures, with LZ and ETC needing as low as 10 samples, whereas SampEn requires at least 80 samples. Our study indicates that complexity measures such as LZ and ETC are good candidates for the analysis of cardiovascular dynamics since they are able to work with very short RR tachograms.

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Section: Introductionmentioning

confidence: 99%

Aging and cardiovascular complexity: effect of the length of RR tachograms

Balasubramanian

Nagaraj

2016

PeerJ

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“…Long term high blood pressure, however, is a major risk factor for coronary artery disease, stroke, heart failure, peripheral vascular disease, vision loss, and chronic kidney disease. [1][2][3] High blood pressure can be categorized as either primary (essential) high blood pressure or secondary high blood pressure. About 90-95% of cases are primary, defined as high blood pressure due to nonspecific lifestyle and genetic factors.…”

Section: Introductionmentioning

confidence: 99%

A Market Survey of Amlodipine (Antihypertensive) in Moradabad City

Jahan

Sahu

2017

Curr. Res. Pharm. Sci.

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A market survey of Amlodipine (Antihypertensive drug) was conducted at several medical shops in Moradabad City. The various brands of Amlodipine are Citanil-T, Amlokind, Omletime, Amodep, Angicam, Lupidip, Amlogen, Amlip etc. are available in selected areas. The Amlokind is more prescribed by doctors. The highest selling brand of Amlodipine is Amlokind. According to medical survey it has been shown that Amlokind (Mankind Pharmaceuticals Pvt Ltd.) is highest selling brand in Moradabad city. Amlodipine is good Antihypertensive drug.

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“…Cardiovascular diseases (CVDs) are a group of diseases affecting the heart and blood vessels and they are the largest cause of morbidity and premature deaths worldwide [1] accounting for 31% of all global deaths in 2012 [2]. The development of CVDs is associated with several risk factors, both modifiable and non-modifiable, and the danger of developing CVD increases considerably with the number of risk factors present [3].…”

Section: Introductionmentioning

confidence: 99%

“…Tobacco smoking, physical inactivity, diabetes mellitus, obesity and overweight are, along with hypertension and dyslipidemia, examples of such preventable risk factors. Although the risk factors associated with the development of CVDs are many and affect several processes in the body, there are two major underlying causes for CVD, namely hypertension and atherosclerosis [1]. Nutritional intervention is well accepted as a safe and effective approach to health maintenance and it has been estimated that a change in nutritional pattern may reduce cardiovascular-related deaths by 60% [4].…”

Section: Introductionmentioning

confidence: 99%

Preclinical and Clinical Studies on Antioxidative, Antihypertensive and Cardioprotective Effect of Marine Proteins and Peptides—A Review

Jensen¹,

Mæhre²

2016

Marine Drugs

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High seafood consumption has traditionally been linked to a reduced risk of cardiovascular diseases, mainly due to the lipid lowering effects of the long chained omega 3 fatty acids. However, fish and seafood are also excellent sources of good quality proteins and emerging documentation show that, upon digestion, these proteins are sources for bioactive peptides with documented favorable physiological effects such as antioxidative, antihypertensive and other cardioprotective effects. This documentation is mainly from in vitro studies, but also animal studies are arising. Evidence from human studies evaluating the positive health effects of marine proteins and peptides are scarce. In one study, a reduction in oxidative stress after intake of cod has been documented and a few human clinical trials have been performed evaluating the effect on blood pressure. The results are, however, inconclusive. The majority of the human clinical trials performed to investigate positive health effects of marine protein and lean fish intake, has focused on blood lipids. While some studies have documented a reduction in triglycerides after intake of lean fish, others have documented no effects.

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Global progress in prevention of cardiovascular disease

Cited by 148 publications

References 17 publications

Aging and cardiovascular complexity: effect of the length of RR tachograms

Aging and cardiovascular complexity: effect of the length of RR tachograms

A Market Survey of Amlodipine (Antihypertensive) in Moradabad City

Preclinical and Clinical Studies on Antioxidative, Antihypertensive and Cardioprotective Effect of Marine Proteins and Peptides—A Review

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