Global research trends in atherosclerosis: A bibliometric and visualized study

Tian, Wende; Zhang, Tai; Wang, Xinyi; Zhang, Jie; Ju, Jianqing; Xu, Hao

doi:10.3389/fcvm.2022.956482

Cited by 9 publications

(5 citation statements)

References 283 publications

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“…Literature was extracted from the WoSCC database and downloaded on August 31, 2022. In order to ensure the highest accuracy and minimum acceptable error, we chose the title search ( 6 ). The search terms were as follows: [TI= (“Insulin Secreting Cells” or “Insulin-Secreting Cells” or “Insulin-Secreting Cell” or “Pancreatic B Cells” or “Pancreatic B Cell” or “Pancreatic beta Cells” or “Pancreatic beta Cell”)] AND [Publication type = (Article or review)] AND [Language = (English)]; Publication data: “1985-01-01” to “2022-08-31”.…”

Section: Methodsmentioning

confidence: 99%

Knowledge domain and emerging trends in beta‐cell research: A bibliometric and knowledge‐map analysis

Luo

Wang²,

Chen³

et al. 2023

Front. Endocrinol.

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BackgroundUp to now, the physiology, pathology, and recovery of beta-cells have been intensively studied and made great progress, and these are of major significance for the treatment of related diseases. Nevertheless, a comprehensive and objective report on the status of beta-cell research is lacking. Therefore, this study aims to conduct a bibliometric analysis to quantify and identify the current status and trending issues in beta-cell research.MethodsThe articles and reviews related to beta-cell were obtained from the Web of Science Core Collection on August 31, 2022. Two scientometric software (CiteSpace 6.1.R3 and VOSviewer 1.6.18) were used to perform bibliometric and knowledge-map analysis.ResultsA total of 4098 papers were published in 810 academic journals in 2938 institutions from 83 countries/regions. The number of beta-cell-related publications was increasing steadily. The United States was the most productive country, while Universite libre de Bruxelles, University of Toronto and University of Geneva were the most active institutions. Diabetes published the most beta-cell studies and received the largest number of co-citations. Decio I Eizirik published the most papers and had the most co-citations. Twelve references on reviews and mechanisms were regarded as the knowledge base. Four major aspects of beta-cell research included the pathological mechanism of beta-cell failure, the recovery of beta cells, the risk factor related to beta cells, and the physiology of beta cells. Endoplasmic reticulum stress and oxidative stress have been core elements throughout the research in this field. In addition, beta-cell dedifferentiation, inflammation, autophagy, miRNA, and lncRNA are hot topics nowadays. Additionally, stem cell replacement therapies might be the alternative way to reverse beta-cell failure. Restoring beta-cell mass and function will remain a research goal in the future.ConclusionThis study provided a comprehensive overview of beta-cell research through bibliometric and visual methods. The information would provide helpful references for scholars focusing on beta cells.

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Section: Methodsmentioning

confidence: 99%

Knowledge domain and emerging trends in beta‐cell research: A bibliometric and knowledge‐map analysis

Luo

Wang²,

Chen³

et al. 2023

Front. Endocrinol.

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“…However, the regulation and implementation of autophagy can be altered as cells age [110]. In cells involved in the pathogenesis of atherosclerosis, the intensity of autophagy/mitophagy tends to increase, and the disruption of this process contributes to atheromatosis and its complications [111][112][113]. Adequate autophagy, proportional to the degree of damage, is an adaptive process in atherosclerosis.…”

Section: Universal Links Of Cs In Atherosclerosismentioning

confidence: 99%

Atherosclerosis and Inflammation: Insights from the Theory of General Pathological Processes

Gusev

Sarapultsev

2023

IJMS

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Recent advances have greatly improved our understanding of the molecular mechanisms behind atherosclerosis pathogenesis. However, there is still a need to systematize this data from a general pathology perspective, particularly with regard to atherogenesis patterns in the context of both canonical and non-classical inflammation types. In this review, we analyze various typical phenomena and outcomes of cellular pro-inflammatory stress in atherosclerosis, as well as the role of endothelial dysfunction in local and systemic manifestations of low-grade inflammation. We also present the features of immune mechanisms in the development of productive inflammation in stable and unstable plaques, along with their similarities and differences compared to canonical inflammation. There are numerous factors that act as inducers of the inflammatory process in atherosclerosis, including vascular endothelium aging, metabolic dysfunctions, autoimmune, and in some cases, infectious damage factors. Life-critical complications of atherosclerosis, such as cardiogenic shock and severe strokes, are associated with the development of acute systemic hyperinflammation. Additionally, critical atherosclerotic ischemia of the lower extremities induces paracoagulation and the development of chronic systemic inflammation. Conversely, sepsis, other critical conditions, and severe systemic chronic diseases contribute to atherogenesis. In summary, atherosclerosis can be characterized as an independent form of inflammation, sharing similarities but also having fundamental differences from low-grade inflammation and various variants of canonical inflammation (classic vasculitis).

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“…Bibliometric and visualization analyses based on mathematical and statistical methods depict the knowledge structures and trends to identify the most prolific countries or regions, institutions, authors, journals, and references, determine rate of the international cooperation and geographic distributions, [17,18] and estimate hotspots and emerging trends in research from references and keywords, [19,20] providing valuable information and direction for further research. [21] The most commonly used bibliometric and visualization statistical analysis software are Cite Space and VOS viewer.…”

Section: Introductionmentioning

confidence: 99%

A bibliometric and visualization study of Meniere’s disease: Current status and global hotspots and emerging trends

Wang

Zhang

et al. 2023

Medicine

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Background: Meniere's disease (MD) is a clinical condition characterized by endolymphatic hydrops. Persistent symptoms negatively affect patients mood, and the underlying etiology remains unclear. It is necessary to comprehensively understand the relevant publications, review the history and current status of research, and analyze hotspots and frontiers of research on MD.Methods: We retrieved literature on Meniere's disease from 2003 to 2022 from the Web of Science database and extracted the data. Data visualization and analysis was conducted using Cite Space, VOS viewer, an online web tool, and Microsoft Office Power Point 2019.Results: In total, 2847 publications were analyzed. The number of annual publications was relatively stable, with an accelerated upward trend over the past 5 years. The country with the most publications was USA (751, 26.38%), while the University of Munich contributed more publications than any other institution (117, 4.11%). The article titled "Diagnostic criteria for Meniere's disease" by Lopez-Escamez J et al in 2015 was the most cited and co-cited publication, and also had the top co-cited references with the strongest citation bursts. Naganawa S was the author with the most publications (85, 2.99%). The top 3 journals and co-cited journals were Otology Neurotology, Acta Oto Laryngologica, and Laryngoscope. Recently, the key theme words were "sensorineural hearing loss," "therapy," "intratympanic injection method," "vestibular-evoked myogenic potentials," "vestibular migraine," "magnetic resonance imaging," and "meniere's disease." Conclusions:The US has the largest number of publications and research institutions, many European countries have highquality journals, and Japan has the highest number of scholars. The international opinion on Meniere's disease is relatively uniform. The stepped-therapy for MD is scientific and clear. Intratympanic injection of steroids and intratympanic injection of gentamicin are commonly used, but steroids are considered safer. Saccular dysfunction may be more common in patients with MD than in those with utricular dysfunctions. It is worth paying attention to study the relationship between MD and vestibular migraine through headache. Progress in magnetic resonance imaging technology is still required for the imaging diagnosis of MD.

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Global research trends in atherosclerosis: A bibliometric and visualized study

Cited by 9 publications

References 283 publications

Knowledge domain and emerging trends in beta‐cell research: A bibliometric and knowledge‐map analysis

Knowledge domain and emerging trends in beta‐cell research: A bibliometric and knowledge‐map analysis

Atherosclerosis and Inflammation: Insights from the Theory of General Pathological Processes

A bibliometric and visualization study of Meniere’s disease: Current status and global hotspots and emerging trends

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