We study the Cauchy problem for the inhomogeneous non linear Landau equation with Maxwellian molecules. In perturbation framework, we establish the global existence of solution in spatially critical Besov spaces. Precisely, if the initial datum is a a small perturbation of the equilibrium distribution in the Chemin-Lerner space L 2 v (B 3/2 2,1 ), then the Cauchy problem of Landau equation admits a global solution belongs to L ∞ t L 2 v (B 3/2 2,1 ). The spectral property of Landau operator enables us to develop new trilinear estimates, which leads to the global energy estimate.2010 Mathematics Subject Classification. Primary: 35H20, 35E15; Secondary:76P05, 82C40.