Glomus Tumor of the Neck Detected With 99mTc EDDA HYNIC-TOC

Abstract

A 54-year-old woman was referred to thyroid evaluation because of a lump on the left side of the neck. Ultrasound exam did not show any thyroid abnormality, but highly perfused nodule at the left common carotid artery bifurcation was found. Because of the specific location, somatostatin receptor scintigraphy with Tc EDDA HYNIC-TOC was performed, starting with perfusion images and followed with SPECT/CT imaging at 2 and 4 hours. Well-perfused nodule with intensive accumulation and no other visible pathology in the body raised suspicion of a glomus tumor, consistent with MR exam performed later. Subsequent surgical removal confirmed carotid paraganglioma.

Hybrid SPECT/CT Somatostatin Receptor Imaging of Neuroendocrine Tumours

“…Većina primarnih i sekundarnih lezija bila je vidljiva već u ranoj fazi snimanja, odmah po aplikaciji radiofarmaka, što upućuje da su lezije pojačano vaskularizirane. S obzirom na to da o procjeni prokrvljenosti NET lezija SR SPECT/CT-om nismo našli podataka, osim vlastitog prikaza slučaja 16 , rezultat nije moguće usporediti s literaturom, no postoje radovi o drugim vrstama tumora koji su dokazali da je pojačana prokrvljenost, detektirana drugim slikovnim dijagnostičkim metodama, povezana s biološkom agresivnošću tumora 17 . Stoga bi bilo korisno u daljnjim istraživanjima podatak o prokrvljenosti primarnog tumora i metastaza usporediti s markerima vezanim uz prokrvljenost, a koji se mogu dobiti patohistološkom analizom te indirektno upućuju na agresivnost tumora (tumorska neoangiogeneza i sl.)…”