Glomus tumors of the stomach

Kay, Saul; Callahan, William P.; Murray, Margaret R.; Randall, Henry T.; Stout, Arthur Purdy

doi:10.1002/1097-0142(195107)4:4<726::aid-cncr2820040410>3.0.co;2-z

Cited by 74 publications

(27 citation statements)

References 1 publication

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“…Although these methods may be helpful for preoperative evaluation, a high index of suspicion is needed and glomus tumours are commonly diagnosed histologically after surgical resection. Glomus tumours stain positive for ɑ-smooth muscle actin, calponin and vimentin, however, unlike GISTs they are negative for CD117 (C-KIT) 11. Operative intervention should be carefully planned.…”

Section: Discussionmentioning

confidence: 99%

Glomus tumour of the stomach: an unusual cause of gastrointestinal bleeding

et al. 2012

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Glomus tumours are a rare type of subepithelial mesenchymal tumours that present in deep visceral organs such as the stomach, which are difficult to diagnose. We report a case of a 44-year-old woman with diabetes who presented with anaemia, abdominal pain and melena diagnosed preoperatively with a gastric glomus tumour initially misdiagnosed as a gastric ulcer located at the lesser curvature. Upon referral to our centre a repeat endoscopy and biopsy were performed. A partial gastrectomy was performed with no complications. Histopathological analysis of the tumour reported clear margins and immunostaining was positive for smooth muscle actin and collagen IV. The patient remains asymptomatic at 3-month follow-up.

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Section: Discussionmentioning

confidence: 99%

Glomus tumour of the stomach: an unusual cause of gastrointestinal bleeding

et al. 2012

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“…Unlike carcinoid tumors, which stain positive LK2H10 (chromogranin) and synaptophysin, glomus tumors never stain positive for chromogranin and are only focally positive for synaptophysin [2].…”

Section: Discussionmentioning

confidence: 97%

“…The majority of glomus tumors occur in the distal extremities, classically in the subungual areas [1]. Kay and colleagues were the first to report glomus tumors in the stomach in 1951 [2]. They are most commonly found in the antrum and have a predilection for the greater curve [1].…”

Section: Discussionmentioning

confidence: 99%

“…Patients can present with symptoms of gastrointestinal bleeding or ulcer-like epigastric pain; however, a significant number are found incidentally on endoscopy [3]. Miettenin and colleagues reported a significant female predominance, but this is less prominent in other large case series [2]. Median age of presentation is 54 years, but a wide range of ages has been reported [2].…”

Section: Discussionmentioning

confidence: 99%

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Laparoscopic Resection of a Gastric Glomus Tumor

et al. 2011

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Surgeons are commonly asked to evaluate patients with subepithelial masses of the stomach. Glomus tumors are subepithelial mesenchymal tumors that are rarely included in the differential diagnosis when evaluating these patients. We present the case of 55-year old man with a gastric glomus tumor that was diagnosed preoperatively and removed by laparoscopic wedge resection. We review the preoperative evaluation and classic finding associated with this uncommon entity.

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“…Visceral involvement is extremely rare as glomus bodies are virtually non-existent and only a limited number of cases have been reported in the English literature [1][2][3][4][5]. Gastric GT was first reported by Kay S et al, in 1951 and till date less than 100 cases have surfaced thereafter in the English literature as they are greatly outnumbered in frequency by other mesenchymal gastric tumours, most commonly GISTs [3]. Miettinen M et al, reported the largest case series and observed gastric GTs to be 100 times rarer than gastric GISTs [2].…”

Section: Discussionmentioning

confidence: 99%