Glomus tumour of the stomach: an unusual cause of gastrointestinal bleeding

Diaz-Zorrilla, Carmina; Grube-Pagola, Peter; Troche, José María Remes; Medina, Antonio Ramos-De la

doi:10.1136/bcr-2012-007391

Cited by 5 publications

(3 citation statements)

References 11 publications

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“…Gastric GTs usually present as asymptomatic. Clinical manifestation may include specific symptoms, including epigastric pain, nausea or vomiting, ulcerous syndrome, and rarely upper gastrointestinal bleeding may be the leading clinical manifestation [10], [11], [12]. Radiological findings show enhancement on the arterial phase, as GTs are hypervascular tumors, with sharp demarcation corroborating our case findings.…”

Section: Discussionsupporting

confidence: 85%

Rare malignant glomus tumor of the stomach with liver metastases

Toti

Manzia

Roma³

et al. 2019

Radiology Case Reports

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We report a case of a 72-year-old male admitted in our Unit with anemia and a 10 cm liver neoplasm. Computed tomography scan showed 2 lesions respectively in the II, III and, VIII segment of the liver. Surgical resection of the larger liver mass was performed and the tumor appeared as a solid-cystic mass and a diagnosis of malignant mesenchymal tumor not otherwise specified, was made. One month later a Computed tomography scan detected a dishomogeneous gastric mass, 6 cm in diameter, in the greater curvature, confirmed by esophagogastroduodenoscopy. The pathological diagnosis from endoscopic biopsy revealed a mesenchymal tumor requiring surgical removal for accurate diagnosis. The patient underwent relaparotomy and gastric resection and the pathological findings gave a diagnosis of a rare malignant glomic tumor of the stomach confirmed by the revision of previously performed hepatic resection classified as secondary lesion.

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Section: Discussionsupporting

confidence: 85%

Rare malignant glomus tumor of the stomach with liver metastases

Toti

Manzia

Roma³

et al. 2019

Radiology Case Reports

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“…Patients are usually asymptomatic at the time of identification [ 11 , 14 ]. Clinical symptoms may include epigastric pain, nausea, vomiting, fatigue, ulcerous syndrome, black stools, and, rarely, upper gastrointestinal bleeding [ 1 – 4 , 19 , 20 ]. In the case of our patient, two of these clinical symptoms were present.…”

Section: Discussionmentioning

confidence: 99%

Gastric glomus tumor: a case report and review of the literature

et al. 2021

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Introduction Gastric glomus tumor is a rare mesenchymal neoplasm. There are only a few cases of the tumor showing malignancy, and there are no specific guidelines for the management of this entity. Case presentation We present the case of a 53-year-old Caucasian male who was hospitalized for anemia. Computerized tomography of the abdomen depicted a mass between the pylorus of the stomach and the first part of the duodenum. Preoperative diagnosis was achieved with pathology examination of the biopsies taken via endoscopic ultrasound and upper gastrointestinal endoscopy. An antrectomy with Roux-en-Y anastomosis and appendicectomy, due to suspicion of appendiceal mucocele, were performed. The patient had an uneventful postoperative recovery and was discharged 5 days later. Discussion Preoperative diagnosis of a gastric glomus tumor is difficult owing to the location of the tumor and the lack of specific clinical and endoscopic characteristics. Furthermore, it is exceptional to establish diagnosis with biopsies taken through endoscopic ultrasound or upper gastrointestinal endoscopy, prior to surgical resection. Although most glomus tumors are benign and are not known to metastasize, there are rare examples of glomus tumors exhibiting malignancy. Treatment of choice is considered wide local excision with negative margins. However, long-term follow-up is required as there is the possibility of malignancy. Conclusion The aim of this report is to enlighten doctors about this uncommon pathologic entity. Surgical resection is considered the golden standard therapy to establish a diagnosis and evaluate the malignant potential.

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“…Additionally, gastric SMTs such as GISTs generally occur in elderly patients, especially in patients above the age of 60; by comparison, this case involved a 24-year-old patient. Although the scarcity of reports may preclude a predictive conclusion, gastric GTs have been reported to occur at younger ages than GISTs, with a median age of 45 years (range, 28–79 years) [ 12 ]. Gastric GT should be included as a differential diagnosis if a solitary, hypervascular SMT is detected in the stomach, especially when it presents with exsanguinating gastrointestinal hemorrhaging and occurs in a young patient.…”

Section: Discussionmentioning

confidence: 99%

Gastric Glomus Tumor: A Rare Cause of Upper Gastrointestinal Bleeding

Handa

Kano

Kaneko

et al. 2015

Case Reports in Surgery

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A 24-year-old woman was referred to our department because of melena. These symptoms combined with severe anemia prompted us to perform an emergency upper endoscopy, which showed bleeding from an ulcerated 30 mm submucosal tumor in the gastric antrum. A computed tomography scan revealed a homogeneously enhanced mass, and endoscopic ultrasonography identified a well-demarcated mass in the third and fourth layers of the gastric wall. Because analysis of the possible medical causes remained inconclusive and the risk of rebleeding, laparoscopy-assisted gastric wedge resection was performed after administration of 10 units of red cell concentrate. Histological and immunohistological analysis revealed the tumor to be a gastric glomus tumor. Gastric submucosal tumors remain challenging to diagnose preoperatively as they show a variety of radiologic and clinicopathologic features and are associated with the risk of bleeding upon biopsy, as is indicated in the guidelines for gastric submucosal tumors. Gastric glomus tumors characteristically present with exsanguinating gastrointestinal hemorrhaging that often requires blood transfusion. Additionally, gastric submucosal tumors typically occur in elderly patients; however, this case involved a young patient who was 24 years old. Here, we describe this case in order to identify features that may aid in early differentiation of gastric submucosal tumors.

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Glomus tumour of the stomach: an unusual cause of gastrointestinal bleeding

Cited by 5 publications

References 11 publications

Rare malignant glomus tumor of the stomach with liver metastases

Rare malignant glomus tumor of the stomach with liver metastases

Gastric glomus tumor: a case report and review of the literature

Gastric Glomus Tumor: A Rare Cause of Upper Gastrointestinal Bleeding

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