Glomus tumour of the colon: dynamic contrast-enhanced CT findings and review of the literature

Tan, Tien Jin; Hayes, Malcolm; Radigan, Jordan; Munk, Peter L.

doi:10.1016/j.clinimag.2015.02.015

Cited by 6 publications

(4 citation statements)

References 12 publications

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“…5 Since then, only 4 additional cases were reported. 4,[6][7][8] The clinical and histopathologic features of those cases, including the current one, are summarized in Table 1. As seen, for all 6 cases, the median age was 45 (range = 34-74) years.…”

Section: Discussionmentioning

confidence: 99%

“…Yet a potential pitfall to keep in mind is that some glomus tumor, including a primary colonic glomus tumor, can stain positive for synaptophysin. 8 The pathogenesis of glomus tumors is still not clear. Multiple familial glomus tumors occur due to inactivating mutations in the glomulin gene.…”

Section: Discussionmentioning

confidence: 99%

“…4 The colon is an extremely rare site for glomus tumor, with only 5 cases been reported so far in the literature. [4][5][6][7][8] Herein, we describe a sixth case of primary colonic glomus tumor to recapitulate the importance of recognizing this rare benign entity in GI tract and utilizing immunostains for proper diagnosis. A brief review of all 6 colonic glomus tumors is performed to summarize its clinicopathologic features.…”

Section: Introductionmentioning

confidence: 99%

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Glomus Tumor of the Colon: A Rare Case Report and Review of Literature

2020

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Glomus tumor is a rare mesenchymal neoplasm originating from the modified smooth muscle cells of the glomus body. Primary colonic glomus tumor is extremely rare with only 5 cases published in the English literature. In this article, we report the sixth case of primary colonic glomus tumor in a 50-year-old female with no significant past medical history who presented with routine screening colonoscopy. The entire colon was endoscopically unremarkable except an incidental 6-mm sessile polyp located in the descending colon. Biopsy showed a densely cellular neoplasm composed of small, bland, slightly spindled to predominantly epithelioid cells with clear to eosinophilic cytoplasm arranged in nests and sheets. The tumor cells were interspersed with slit-like thin-walled vessels and scattered short nerve bundles. Immunohistochemically, the tumor cells were positive for smooth muscle actin, h-caldesmon, and CD34 (focal), but completely negative for HMB45, S100, EMA, desmin, DOG-1, and CD117. The histologic features and immunohistochemical profile supported a diagnosis of primary colonic glomus tumor. The patient was asymptomatic and disease free after the procedure.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Glomus Tumor of the Colon: A Rare Case Report and Review of Literature

2020

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“…Прерывистое периферическое узловое усиление образования толстой кишки с последующим центро стремительным заполнением контрастом напоминало гемангиому печени и не было ранее описано при гломусной или какой-либо другой субэпителиальной опухоли толстой кишки. Авторы считают, что обнаружение этого паттерна усиления опухоли повышает вероятность выявления гломусной опухоли толстой кишки до гистологического подтверждения [72]. Таким образом, МСКТ-признаки гломусной ангиомы вариабельны и недостаточно изучены на настоящее время.…”

Section: гломусная ангиома мягких тканей конечностейunclassified

Glomus angioma: series of cases and literature review

Stepanova,

Glotov,

Shirokov

et al. 2023

Medicinskaâ vizualizaciâ

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Glomus tumors usually occur in areas rich in glomus bodies, such as the subungual areas of the fingers or the deep dermis of the palm, wrist, and forearm, but they can also occur in deep visceral sites throughout the body, including the lungs, stomach, pancreas, liver, gastrointestinal and urinary tracts. They are thought to have originated from modified smooth muscle cells of the neuromyoarterial glomus, commonly referred to as the glomus body, whose function is to regulate temperature through arteriovenous shunting of the blood. Important during the pathological process for these tumors are pain that persists for a long time, which is often necessary for their detection and the possibility of relapse.The purpose: to analyze and evaluate our own clinical cases of glomus angioma of various localization.Materials and methods. 6 patients with a morphologically verified diagnosis of glomus angioma (5 women and 1 man aged 23 to 50 years, mean age 34.5 years) were treated at A.V. Vishnevsky National Medical Research Center of Surgery for the period from 2004 to 2023. All patients were operated on. Lesions localization: limbs soft tissues – 3, retroperitoneal space – 2, lung – 1.Results. The term of the lesions detection varied from 2 months to congenital. In 2 of 3 cases of the limbs soft tissues tumors localization they were congenital. Limbs soft tissues glomus tumors: the leions ranged in size from 40.0 × 28.65 mm to a large lesion, consisting of multiple foci ranging in size from 20.0 to 60.0 mm in diameter, all tumors were multinodular. Retroperitoneal glomus tumors: the lesions were rather large (a multinodular lesion from 6.0 to 48.0 mm in diameter and a single-nodular multi-chamber lesion of a polycyclic form, 150.0 × 100.0 × 80.0 mm in size). The lung glomus tumor was single-nodular and had a diameter of 12.5 mm. In the vast majority of cases (5/6), the lesions manifested with the pain and discomfort. Only the lung lesion was detected by chance and during a routine examination.The criteria for ultrasound and MSCT signs of the lesions of various localizations are given. The data are compared with literature data.Conclusion. Given the rarity of glomus angioma and the lack of publications on glomus angiomas of soft tissues of the extremities and deep-seated tumors in the domestic literature, the presented analysis of a series of our own cases will increase the awareness of clinicians and diagnosticians about these tumors and, thereby, increase their detection, which will allow for earlier surgery.

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