Glucocorticoid-Induced Thymocyte Death in the Murine Thymus: The Effect at Later Stages.

Ishii, Tadashi; Nakamura, Masanori; Yagi, Hideki; Soga, Hiroyuki; Kayaba, Shoichi; Gotoh, Takahiro; Satoh, Susumu; Itoh, Takeshi

doi:10.1679/aohc.60.65

Cited by 16 publications

(7 citation statements)

References 18 publications

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“…Since not only macrophages but also thymic nurse cells have been shown to recognise and ingest apoptotic cells [27], our observations suggest an increase in the number of nurse cells/macrophages phagocytosing apoptotic thymocytes in P rats. As expected [28], "free" annexin V + thymocytes were hardly detectable in both S and P rats.…”

Section: Annexin-fitc Stainingsupporting

confidence: 83%

Long‐term β‐adrenergic receptor blockade increases levels of the most mature thymocyte subsets in aged rats

Pešić¹,

Plećaš-Solarović²,

Radojević³

et al. 2007

International Immunopharmacology

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Section: Annexin-fitc Stainingsupporting

confidence: 83%

Long‐term β‐adrenergic receptor blockade increases levels of the most mature thymocyte subsets in aged rats

Pešić¹,

Plećaš-Solarović²,

Radojević³

et al. 2007

International Immunopharmacology

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“…Stress responses of animals are excited mainly by the activation of hypothalamic-pituitary-adrenal (HPA) axis and the adrenocorticotrophic nervous system (Ishii et al, 1997). HPA axis is the stress response modulator, which transformed the nerve, endocrine and the cell factor information as the physiological reaction.…”

Section: Discussionmentioning

confidence: 99%

Traditional Chinese Medicine Prescriptions Enhance Growth Performance of Heat Stressed Beef Cattle by Relieving Heat Stress Responses and Increasing Apparent Nutrient Digestibility

Song¹,

Luo²,

et al. 2014

Asian Australas. J. Anim. Sci

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The present aim was to investigate the effects of traditional Chinese medicine prescriptions (TCM) on body temperature, blood physiological parameters, nutrient apparent digestibility and growth performance of beef cattle under heat stress conditions. Twenty-seven beef cattle were randomly divided into three groups as following; i) high temperature control (HTC), ii) traditional Chinese medicine prescriptions I+high temperature (TCM I) and iii) traditional Chinese medicine prescriptions II+high temperature (TCM II) (n = 9 per group). The results showed that the mean body temperature declined in TCM II treatment (p<0.05). Serum T3 and T4 levels with TCM I and TCM II treatments elevated (p<0.05), and serum cortisol levels of TCM I treatments decreased (p<0.05), compared with the HTC group. Total protein, albumin, globulin in TCM II treatments elevated and blood urea nitrogen levels of both TCM treatments increased, but glucose levels of both TCM treatments decreased, compared with the HTC group (p<0.05). The apparent digestibility of organic matter and crude protein with TCM I treatment increased, and the apparent digestibility of acid detergent fiber elevated in both TCM treatments (p<0.05). Average daily feed intake was not different among three groups, however average daily gain increased and the feed:gain ratio decreased with both TCM treatments, compared with the HTC group (p<0.05). The present results suggest that dietary supplementation with TCM I or TCM II improves growth performance of heat stressed beef cattle by relieving heat stress responses and increasing nutrient apparent digestibility.

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“…animals are activated mainly by the regulation of hypothalamic-pituitary-adrenal (HPA) axis and adrenocorticotrophic nervous system (Ishii et al, 2011). Increasing evidences have suggested that as an endogenous refrigerant, GABA could reduce the activity of HPA axis directly and regulate the body's energy expenditure of heat-stressed animals (Frosini, 2007;Marques de Souza & Franci, 2008).…”

mentioning

confidence: 99%

The anti–heat stress effects of Chinese herbal medicine prescriptions and rumen‐protected γ‐aminobutyric acid on growth performance, apparent nutrient digestibility, and health status in beef cattle

Chen

Guo

Song

et al. 2020

Animal Science Journal

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The high temperature and humid weathers coupled with low wind speed can induce heat stress in animal, resulting in reduced growth performance, compromised health status, or even death (Mader, Davis, & Brown-Brandl, 2006). Heat stress is known to disturb metabolic and physiological processes required for optimal cattle productivity, as well as cattle immunity (Collier, Collier, Rhoads, & Baumgard, 2008; Rhoads et al., 2009; West, 2003). Previous studies demonstrated that heat stress lowers average daily feed intake (ADFI) and average daily gain (ADG), which significantly increases breeding cost and compromises production profit (Piotr, Sabina, & Jacek, 2018; Polsky & Von Keyserlingk, 2017). Therefore, it is necessary to develop anti-heat stress therapy to improve the cattle production efficiency. Natural products, such as traditional Chinese herbal medicine (CHM) and γ-aminobutyric acid (GABA), have received remarkable attention due to their anti-heat stress potential (Song, Xu, Wang, &

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Glucocorticoid-Induced Thymocyte Death in the Murine Thymus: The Effect at Later Stages.

Cited by 16 publications

References 18 publications

Long‐term β‐adrenergic receptor blockade increases levels of the most mature thymocyte subsets in aged rats

Long‐term β‐adrenergic receptor blockade increases levels of the most mature thymocyte subsets in aged rats

Traditional Chinese Medicine Prescriptions Enhance Growth Performance of Heat Stressed Beef Cattle by Relieving Heat Stress Responses and Increasing Apparent Nutrient Digestibility

The anti–heat stress effects of Chinese herbal medicine prescriptions and rumen‐protected γ‐aminobutyric acid on growth performance, apparent nutrient digestibility, and health status in beef cattle

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