Glutathione peroxidase activity and selenium concentration in bovine blood and liver as indicators of dietary selenium intake

Thompson, K. G.; Fraser, A.J.; Harrop, Brynn; Kirk, J. A.; Bullians, J.; Cordes, D. O.

doi:10.1080/00480169.1981.34776

Cited by 45 publications

(19 citation statements)

References 16 publications

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“…Serum (or plasma) Se concentration also responds more quickly than whole blood Se to changes in dietary Se concentration (Thompson et al 1980(Thompson et al , 1981. In the present study, serum Se concentration remained unchanged from 30 d before the expected calving date and at calving (Table 3), which corresponded to the weeks with the lowest Se intake.…”

Section: Koenig and Beauchemin * Organic Selenium Yeast For Dairy Cowsupporting

confidence: 50%

Supplementing selenium yeast to diets with adequate concentrations of selenium: Selenium status, thyroid hormone concentrations and passive transfer of immunoglobulins in dairy cows and calves

Koenig¹,

Beauchemin²

2009

Can. J. Anim. Sci.

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Holstein (primipares et multipares) une ration mixte enrichie avec 0,3 mg de Se par kg (de matie`re se`che), soit sous forme de levure, soit sous forme de se´le´nite de sodium 60 jours avant la date pre´vue du veˆlage jusqu'au 60 e jour de lactation. Les animaux avaient rec¸u une ration contenant 0,38 a`0,40 mg de Se par kg, sans supple´ment de Se pendant les 90 jours pre´ce´dant le traitement. La teneur en Se de la ration enrichie variait de 0,62 a`0,81 mg par kg. Les auteurs ont pre´leve´du sang des vaches 60 et 30 jours avant la date pre´vue du veˆlage, au veˆlage ainsi qu'au 15 e , au 30 e et au 60 e jour de lactation; les pre´le`vements sanguins sur les veaux ont e´te´effectue´s a`l'aˆge de 24 h et de 56 jours. Le lait a e´te´recueilli au veˆlage (colostrum) ainsi qu'au 15 e , au 30 e et au 60 e jour de lactation. À la naissance, les veaux ont e´te´enleve´s de leur me`re et nourris avec une quantite´de colostrum correspondant a`10 % de leur poids corporel dans les 12 heures qui ont suivi. La concentration de Se dans le sang entier est d'en moyenne 11 % plus e´leve´e (P B0,05) chez les vaches qui ont rec¸u du Se de levure que chez celles qui ont rec¸u du se´le´nite (291 c. 26294,5 ng par mL), tandis que la concentration de cet e´le´ment dans le se´rum est d'en moyenne 13 % plus e´leve´e chez les vaches nourries avec du se´le´nium de levure (128 c. 11395,3 ng par mL). Le se´le´nium de levure fourni a`la me`re rehausse (P B0,05) le bilan du Se des veaux en augmentant la concentration de

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Section: Koenig and Beauchemin * Organic Selenium Yeast For Dairy Cowsupporting

confidence: 50%

Supplementing selenium yeast to diets with adequate concentrations of selenium: Selenium status, thyroid hormone concentrations and passive transfer of immunoglobulins in dairy cows and calves

Koenig¹,

Beauchemin²

2009

Can. J. Anim. Sci.

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“…Thus Thompson et al (1981) obtained the correlation coefficient r = 0.97, Koller et al (1984) Zamorski et al (1995), who investigated the relation between selenium concentration and GSH-Px activity in various species, found significant correlations for cattle (r = 0.63), sheep (r = 0.92), swine (r = 1.0), horses (r = 0.81), and humans (r = 0.88). It can therefore be concluded that our findings confirmed the close correlation between selenium concentration and GSH-Px activity in whole blood.…”

Section: Resultsmentioning

confidence: 99%

Direct and Indirect Assessment of Selenium Status in Cattle - A Comparison

Pavlata¹,

Pechová²,

Illek³

2000

Acta Vet. Brno

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Selenium concentration and activity of glutathione peroxidase (GSH-Px) as direct and indirect indicators of selenium status were determined in whole blood samples collected from 326 cattle in 30 herds kept in various regions of the Czech Republic. The GSH-Px activity in the samples was measured by the UV method, using the set supplied by Randox. Selenium in the sample was measured using the hydride technique AAS. The two variables showed a close and significant correlation (r = 0.90; p < 0.01). The regression line, defined by the equation y = 6.44x + 21.4, allowed us to determine the GSH-Px activity of 665.4 µkat . l -1 as equivalent to selenium concentration in whole blood 100 µg . l -1 . Mean selenium concentration and mean GSH-Px activity found in whole blood samples were 78.25 ± 46.67 µg . l -1 and 525.51 ± 335.56 µkat . l -1 , respectively. Insufficient or marginal supply of selenium was diagnosed in 64% of the animals in terms of selenium concentration, in 63% of the animals in terms of GSH-Px activity and in 55% of the animals with selenium concentrations <100 µg . l -1 and GSH-Px activity < 665.4 µkat . l -1 . In this study, close dependence of GSH-Px activity and selenium concentration in the blood of cattle was found. Activity values of GSH-Px were determined for the use in diagnosis of insufficient selenium in cattle in the Czech Republic.

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“…Differences in the rate of change between tissues, in terms of elemental levels or specific enzyme activity, with increases in trace element intakes are well demonstrated with Se in grazing cattle (Thompson et al 1981). For example, when the changes in the Se concentrations in liver, whole blood, erythrocytes and plasma and the activity of glutathione peroxidase (GSH-px) in erythrocytes and plasma were monitored in calves transferred from a pasture containing 23 ug Se/kg DM (deficient) to one containing 93 ug Se/kg DM (adequate) for 24 weeks, different responses were observed (Thompson et al 1981).…”

Section: Discussionmentioning

confidence: 99%

“…For example, when the changes in the Se concentrations in liver, whole blood, erythrocytes and plasma and the activity of glutathione peroxidase (GSH-px) in erythrocytes and plasma were monitored in calves transferred from a pasture containing 23 ug Se/kg DM (deficient) to one containing 93 ug Se/kg DM (adequate) for 24 weeks, different responses were observed (Thompson et al 1981). The Se concentrations in the liver and plasma, and plasma GSH-px increased and reached a maximum after 12-16 weeks whereas the erythrocyte Se concentration and GSH-px activity were still increasing at 24 weeks.…”

Section: Discussionmentioning

confidence: 99%

Effect of Co, Cu, Fe, Mn, Mo, Se, and Zn supplementation on the elemental content of soft tissues and bone in sheep grazing ryegrass/white clover pasture

Grace¹,

Lee²

1990

New Zealand Journal of Agricultural Research

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, and Mn (l05-455) on the concentrations of major and minor elements in some organs, soft tissues, and bones of 72 Romney wethers were measured. The treatment and two control groups were each made up of six sheep. Trace elements were administered daily for 84 days and the sheep grazed as one group on ryegrass/white clover pasture. The animals were then shorn and slaughtered, and some organs, tissue, and bones removed for elemental analyses. A 40% increase in liver Cu occurred when Cu intakes were increased. The Se contents of the liver, kidney, and plasma were increased by over 200% and wool by 23% with increased Se intake. Similarly, increased Mn intakes increased the Mn contents of the liver, kidney, spleen, brain, and pancreas by over 25% and the gut by 260%, and increased Fe intakes increased the Fe contents of the lungs, spleen, and gut by 30, 57, and 76% respectively. Iron also decreased the Cu contents in the carcass (27%) and, markedly, in the liver (45%). Bone mineral concentrations were influenced by increasing the intakes of Se, Mo, and Cu. The Mo and Se contents of the scapula, humerus, ulna/radius, and rib were increased by over 220 and 35% respectively with increased Mo and Se intakes, and the Ca, P, Mg and Na concentrations of the bone were elevated 16--23, 17-34, 19-27, and 8-18% respectively depending on the particular bone when supplementary Cu was given.

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Glutathione peroxidase activity and selenium concentration in bovine blood and liver as indicators of dietary selenium intake

Cited by 45 publications

References 16 publications

Supplementing selenium yeast to diets with adequate concentrations of selenium: Selenium status, thyroid hormone concentrations and passive transfer of immunoglobulins in dairy cows and calves

Supplementing selenium yeast to diets with adequate concentrations of selenium: Selenium status, thyroid hormone concentrations and passive transfer of immunoglobulins in dairy cows and calves

Direct and Indirect Assessment of Selenium Status in Cattle - A Comparison

Effect of Co, Cu, Fe, Mn, Mo, Se, and Zn supplementation on the elemental content of soft tissues and bone in sheep grazing ryegrass/white clover pasture

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