Glycated proteins: Clinical utility and analytical approaches

Megerssa, Yoseph Cherinet; Tesfaye, Demo Yemane

doi:10.5897/ajbr2014.0802

Cited by 3 publications

(2 citation statements)

References 37 publications

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“…Although diabetes mainly comprises chronic levels of hyperglycemia, many diabetic patients, specifically those with type-2, also found to have raised up in the blood pressure (hypertension), chronic high levels of insulin (hyperinsulinemia) (Yoseph & Demo, 2015) and unnatural levels of cholesterol, triglycerides and/or other blood fats (hyperlipidemia) (Mir et al, 2008). In addition, lipoprotein and hematological abnormalities are among the most common complications related to type 2 diabetes.…”

Section: Introductionmentioning

confidence: 99%

Antioxidant and Antihyperglycemic Activity of Arthrospira platensis (Spirulina platensis) Methanolic Extract: In vitro and In vivo Study

et al. 2020

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Section: Introductionmentioning

confidence: 99%

Antioxidant and Antihyperglycemic Activity of Arthrospira platensis (Spirulina platensis) Methanolic Extract: In vitro and In vivo Study

et al. 2020

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“…This was previously reported in some of the marine algae such as Sargassum ringgoldianum, S. wightii and Ulva fasciata [36,37]. The free amino group of hemoglobin (Hb) reacted with glucose is a non-enzymatic reaction that produces HbA1c (glycated haemoglobin) [38]. The decrease in Hb and increase in HbA1c is directly proportional to the blood glucose levels [39].…”

Section: Discussionmentioning

confidence: 89%

Protective role of marine macroalgae extracts against STZ induced diabetic rats

Rayapu¹,

Makkar²,

Anandan³

et al. 2017

JCLM

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Correlation between glycated hemoglobin and venous blood sugar in diabetic patients monitored in Abidjan

Absalome¹,

Camara-Cisse²,

Gervais³

et al. 2020

Afr. J. Biochem. Res.

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The aim of this study was to determine the correlation between glycated hemoglobin and blood sugar levels in diabetic subjects carried out in Abidjan. This cross-sectional study included 100 patients with diabetes monitored, for three months, for whom glycated blood glucose and hemoglobin were performed, this after informed consent of the patients. Pearson and Spearman correlation tests were used, at the 5% threshold. The patients with normal HbA1C and normal blood glucose accounted for 55.34 and 32%, respectively. A sedentary lifestyle and body mass index > 25 kg/m² were associated with a significant increase in the risk of increased blood glucose and HbA1C. The presence of a complication was associated with a 3.06-fold higher risk of high glycated hemoglobin (p= 0.0073), while blood glucose was not significantly associated with the onset of complications. Glycated hemoglobin was significantly correlated with blood glucose with a correlation coefficient of 0.4412 (p 0.0001). In multivariate analysis, hyperglycemia was significantly associated with alcohol consumption and noncompliance with antidiabetic treatment. Poor compliance was significantly associated with increased glycated hemoglobin (>7%) and tobacco consumption. The glycated hemoglobin was highly correlated with blood sugar, and was found to be a better predictor of diabetes complications than glycemia.

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Glycated proteins: Clinical utility and analytical approaches

Cited by 3 publications

References 37 publications

Antioxidant and Antihyperglycemic Activity of Arthrospira platensis (Spirulina platensis) Methanolic Extract: In vitro and In vivo Study

Antioxidant and Antihyperglycemic Activity of Arthrospira platensis (Spirulina platensis) Methanolic Extract: In vitro and In vivo Study

Protective role of marine macroalgae extracts against STZ induced diabetic rats

Correlation between glycated hemoglobin and venous blood sugar in diabetic patients monitored in Abidjan

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