Glycolipid biosurfactants: Potential related biomedical and biotechnological applications

Photomodulation of bacterial growth and biofilm formation using carbohydrate-based surfactants

“…In particular, microbial glycolipids and their synthetic analogues have attracted considerable interest as selective antibacterial agents and as mechanistic tools for expanding our understanding of bacterial physiology and biofilm formation. 3,4 In many cases, this bioactivity can be attributed to the ability of these molecules to lower interfacial tension, thereby mediating bacterial motility, cellular and protein adhesion, signalling and communication, pH regulation, nutrient uptake, and degradation of harmful metabolites. 3–6 These multifaceted responses are dependent on the bacterial strain and surfactant used, and our current understanding is limited to a handful of well-characterized systems.…”

“…3,4 In many cases, this bioactivity can be attributed to the ability of these molecules to lower interfacial tension, thereby mediating bacterial motility, cellular and protein adhesion, signalling and communication, pH regulation, nutrient uptake, and degradation of harmful metabolites. 3–6 These multifaceted responses are dependent on the bacterial strain and surfactant used, and our current understanding is limited to a handful of well-characterized systems. Access to chemical tools with tuneable properties that could selectively influence bacterial growth and biofilm formation offers new opportunities to develop novel therapies for biofilm-associated diseases, and to study the mechanisms governing bacterial adhesion and biofilm formation.…”

Advances in applications of rhamnolipids biosurfactant in environmental remediation: A review

“…This ability has been shown by the study where the water–air surface tension decreased from 72 mN/m to values below 30 mN/m, and from 43 mN/m to values below 1 mN/m for the water‐oil interfacial tension with addition of rhamnolipids (Soberón‐chávez & Maier, ). These unique properties make rhamnolipids suitable for use in diverse industrial and environmental applications (Hallmann & Mędrzycka, ; Inès & Dhouha, ; Nitschke et al, ; Zhong, Yang, et al, ).…”

“…Due to the advantages in physicochemical and biological properties, rhamnolipids are widely used in many fields, such as environmental remediation, oil recovery, food production, cosmetics, and pharmaceutics (Amani, ; Amani, Müller, Syldatk, & Hausmann, ; Bachmann, Johnson, & Edyvean, ; Bharali, Saikia, Ray, & Konwar, 2013; Christova et al, ; Dashtbozorg, Miao, & Ju, ; Pornsunthorntawee, Chavadej, & Rujiravanit, ; Vu, Tawfiq, & Chen, ; Yan, Xu, Chen, & Zheng, ). To our knowledge, several good review articles focused on specific topics of rhamnolipids in therapeutic, biomedical, pharmaceutical, and industrial applications have been published (Banat et al, ; Gudiña, Rangarajan, Sen, & Rodrigues, ; Inès & Dhouha, ; Nitschke, Costa, & Contiero, ). Also, several reviews (Abdel‐Mawgoud et al, ; Mao, Rui, Wei, & Yu, ; Mulligan, ; Pacwa‐Płociniczak, Płaza, Piotrowska‐Seget, & Cameotra, ) and book chapters (Açıkel, ; Franzetti et al, ) have summarized the data on the performance of rhamnolipids in enhancing organic contaminated soil and heavy metal contaminated soil remediation.…”

Gate‐to‐gate life cycle assessment of biosurfactants and bioplasticizers production via biotechnological exploitation of fats and waste oils

“…2,3 Bio-based chemicals and materials, produced by biocatalysts such as yeast, bacteria and fungi, have the advantages of being biodegradable, biocompatible and environmentally friendlier than their fossil fuel-derived counterparts. 5,[10][11][12][13][14] Their global market by revenue is projected to reach $2477.4 million by 2020, compared with $1870.1 million in 2013, witnessing a compound annual growth rate (CAGR) of 4.1%. Biotechnological production of biosurfactants is such an example.…”