Gnathostomiasis nach Aufenthalt in Thailand

Jelinek, Thomas; Ziegler, Moritz M.; Löscher, Thomas

doi:10.1055/s-2008-1058879

Cited by 10 publications

(1 citation statement)

References 9 publications

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“…Humans who are accidental hosts of the larvae acquire the infection through eating un‐ or undercooked flesh of fish, chicken, snails, frogs and pigs or ingestion of contaminated water. Rarely, as with other nematodes, larvae can penetrate the skin [3].…”

Section: Discussionmentioning

confidence: 99%

Gnathostomiasis: Import from Laos

Hennies

Jappe

Kapaun

et al. 2006

J Deutsche Derma Gesell

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Gnathostomiasis is a nematode infestation endemic in Southeast Asia, which can involve multiple organs including the liver, eyes, gastrointestinal tract and CNS. The most common manifestation is recurrent migratory subcutaneous swellings which can appear anywhere on the body and are accompanied by pruritus and systemic symptoms such as low-grade fever, loss of appetite and nausea. The diagnosis is based on the clinical picture, history of travel, peripheral blood eosinophilia and the determination of agent-specific antibody levels. The standard treatment is albendazole. We present a 37-year-old Laotian woman, who had lived in Germany for 17 years, but developed recurrent swelling of the cheek following a visit to Laos. Because of the typical clinical findings, the history of a visit to Laos, and the presence of specific anti-Gnathostoma antibodies on Western blot, the diagnosis of cutaneous gnathostomiasis was made.

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Section: Discussionmentioning

confidence: 99%

Gnathostomiasis: Import from Laos

Hennies

Jappe

Kapaun

et al. 2006

J Deutsche Derma Gesell

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Sushi, ceviche and gnathostomiasis - A case report and review of imported infections

Leroy

Cornu

Deleplancque³

et al. 2017

Travel Medicine and Infectious Disease

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Imported cutaneous gnathostomiasis: report of five cases

Ménard

Santos

Dekumyoy

et al. 2003

Transactions of the Royal Society of Tropical Medicine and Hygi

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Gnathostomiasis has rarely been described outside endemic countries. We report on a series of 5 patients (4 females, 1 male, mean age 42.2 years) who returned to France from South-East Asia and presented with cutaneous gnathostomiasis. The cutaneous lesions appeared within a mean period of 62 d (range 10-150 d) after return. They consisted of creeping eruptions in 3 patients (in addition one also had papules, one had nodules and hepatitis, and one had hepatitis; all 3 had profound asthenia) and recurring migratory swellings in 2 patients. The mean eosinophil count was 1546/mm3 (range 398-3245/mm3). Diagnosis was based on positive serological tests in 3 patients and seroconversion in 2 patients, and was confirmed by identification of Gnathostoma hispidum in a biopsy specimen from one of the seropositive patients. Albandazole (1-4 courses) was given as treatment. Recurrences may occur up to 24 months after apparent cure without reinfection. Gnathostomiasis should be considered when patients return from tropical countries and present with migratory swellings or creeping eruption that does not respond to the usual treatment for cutaneous larva migrans. Serological tests may be negative initially and thus need to be repeated to check for seroconversion. Treatment may require multiple courses of albendazole and a prolonged period of follow-up is necessary before cure can be confirmed.

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Gnathostomiasis nach Aufenthalt in Thailand

Cited by 10 publications

References 9 publications

Gnathostomiasis: Import from Laos

Gnathostomiasis: Import from Laos

Sushi, ceviche and gnathostomiasis - A case report and review of imported infections

Imported cutaneous gnathostomiasis: report of five cases

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