Gold nanoparticle based surface enhanced fluorescence for detection of organophosphorus agents

Dasary, Samuel S. R.; Uma, S.; Yu, Hongtao; Anjaneyulu, Y.; Dubey, Madan; Ray, Paresh Chandra

doi:10.1016/j.cplett.2008.05.082

Cited by 84 publications

(40 citation statements)

References 35 publications

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“…The molecular fluorescent probe 29 based on the surface enhancement of fluorescence of gold nanoparticle was presented by Ray's group (Scheme 4) [29]. The solution of Eu(III) ions exhibited five emission bands respectively at about 458, 535, 555, 590, and 615 nm upon the excitation at 395 nm.…”

Section: Fluorescent Molecular Probes For the Detection Of The Cwas Imentioning

confidence: 99%

Fluorescent molecular probes for the detection of chemical warfare agents and their mimics

Bai

Zhang

et al. 2010

Front. Chem. China

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Owing to their direct toxic effects on human beings, animals, and plants, chemical warfare agents (CWAs) and their mimics have become widespread in chemical warfare and agriculture. The considerable concerns about their entry into biological systems and the residues in environment stimulate the development of rapid and sensitive methods for the detection and analysis of this family of compounds. In the progress of sensitive, selective, and fast responsive detection, fluorescent molecular probes have been widely used in the detection of CWAs in recent years. Here the recent reports on the design of fluorescent molecular probes and their advantages in the detection of CWAs were reviewed. Furthermore, the extensive interests accelerate the development of novel fluorescent molecular probes and detection techniques in this field.

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Section: Fluorescent Molecular Probes For the Detection Of The Cwas Imentioning

confidence: 99%

Fluorescent molecular probes for the detection of chemical warfare agents and their mimics

Bai

Zhang

et al. 2010

Front. Chem. China

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“…[13,14] These materials on the metal Abstract: We present herein a simple method for enhancing the emission of DNA intercalators in homogeneous nanobiohybrids of unlabeled oligo-A C H T U N G T R E N N U N G nucleotides and unmodified gold nanoparticles (GNPs). Pristine singlestranded DNA (ss-DNA) has been wrapped around unmodified GNPs to induce metal-enhanced fluorescence (MEF) of DNA intercalators, such as ethidium bromide and propidium iodide.…”

Section: Introductionmentioning

confidence: 99%

Unmodified “GNP–Oligonucleotide” Nanobiohybrids: A Simple Route for Emission Enhancement of DNA Intercalators

Maiti

Dutta

Das

2011

Chemistry A European J

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We present herein a simple method for enhancing the emission of DNA intercalators in homogeneous nanobiohybrids of unlabeled oligonucleotides and unmodified gold nanoparticles (GNPs). Pristine single-stranded DNA (ss-DNA) has been wrapped around unmodified GNPs to induce metal-enhanced fluorescence (MEF) of DNA intercalators, such as ethidium bromide and propidium iodide. The thickness of the ss-DNA layer on the gold nanosurface determines the extent of MEF, since this depends on the position of the intercalator in relation to the metal surface. Presumably, at a suitable thickness of this DNA layer, more of the intercalator is localized at the optimum distance from the nanoparticle to give rise to MEF. Importantly, no external spacer or coating agent was needed to induce the MEF effect of the GNPs. The concentration ratios of Au to DNA in the nanohybrids, as well as the capping agents applied to the GNPs, play key roles in enhancing the emission of the intercalators. The dimensions of both components of the nanobiohybrids, that is, the size of the GNPs and the length of the oligonucleotide, have considerable influences on the emission enhancement of the intercalators. Emission intensity increased with increasing size of the GNPs and length of the oligonucleotide only when the DNA efficiently wrapped the nanoparticles. An almost 100 % increment in the quantum yield of ethidium bromide was achieved with the GNP-DNA nanobiohybrid compared with that with DNA alone (in the absence of GNP), and the fluorescence emission was enhanced by 50 % even at an oligonucleotide concentration of 2 nM. The plasmonic effect of the GNPs in the emission enhancement was also established by the use of similar nanobioconjugates of ss-DNA with nonmetallic carbon nanoparticles and TiO(2) nanoparticles, with which no increase in the fluorescence emission of ethidium bromide was observed.

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“…An AChE biosensor based on the assembly of multiwall carbon nanotubes onto liposome bioreactors was developed by Yan et al [310] for detection of organophosphates pesticides. On the other hand, Dasary et al [311] developed AuNP-based surface enhanced fluorescence spectroscopy for rapid and sensitive screening of organophosphorus agents with high sensitivity (1 µmol/dm 3 ). They used the fact that Eu(III) ions that are bound within the electromagnetic field of AuNPs exhibit a strong fluorescence enhancement but in the presence of organophosphates Eu(III) ions are released from the AuNP surface, since the binding constant of Eu(III) ion with organophosphates is much higher than that of Eu(III) ion with AuNPs, which results in very distinct fluorescence signal change.…”

Section: Biosensorsmentioning

confidence: 99%

Application Of Nanotechnology In Agriculture And Food Industry, Its Prospects And Risks

Jampílek

Kráľová

2015

Ecological Chemistry and Engineering S

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Nanoagrochemicals, such as nanopesticides, nanofertilizers or plant growth stimulating nanosystems, were primarily designed to increase solubility, enhance bioavailability, targeted delivery, controlled release and/or protection against degradation resulting in the reduced amount of applied active ingredients and finally in a decrease of dose-dependent toxicity/burden. This paper is a comprehensive up-to-date review related to the preparation and the biological activity of nanoformulations enabling gradual release of active ingredient into weeds and the body of pests and controlled release of nutrients to plants. The attention is also devoted to the decrease of direct environmental burden and economic benefits due to application of nanoformulations, where less amount of active ingredient is needed to achieve the same biological effect in comparison with bulk. The application of nanotechnology in the areas such as food packaging, food security, encapsulation of nutrients and development of new functional products is analysed. The use of nanoparticles in biosensors for detection of pathogens and contaminants as well as in DNA and gene delivery is discussed as well. Benefits and health risks of nanoagrochemicals are highlighted, and special attention is given to nanoecotoxicology and guidelines and regulatory documents related to the use of nanoformulations in agriculture and food industry.

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Gold nanoparticle based surface enhanced fluorescence for detection of organophosphorus agents

Cited by 84 publications

References 35 publications

Fluorescent molecular probes for the detection of chemical warfare agents and their mimics

Fluorescent molecular probes for the detection of chemical warfare agents and their mimics

Unmodified “GNP–Oligonucleotide” Nanobiohybrids: A Simple Route for Emission Enhancement of DNA Intercalators

Application Of Nanotechnology In Agriculture And Food Industry, Its Prospects And Risks

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