Gold–silver nanoshells promote wound healing from drug-resistant bacteria infection and enable monitoring via surface-enhanced Raman scattering imaging

He, Jian; Qiao, Yunfei; Zhang, Hongbo; Zhao, Jun; Li, Wanli; Xie, Tingting; Zhong, Danni; Wei, Qiaolin; Hua, Shiyuan; Yu, Yinhui; Yao, Ke; Santos, Hélder A.; Zhou, Min

doi:10.1016/j.biomaterials.2020.119763

Cited by 120 publications

(88 citation statements)

References 48 publications

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“… 7 , 8 Generally, the common SERS substrates are restricted to noble metals, especially Au and Ag, owing to their high enhancement. 9 , 10 Meanwhile, a Ag nanomaterial is a class of typical inorganic antibacterial agents, exhibiting wide-spectra, and durable and efficient antibacterial properties against bacteria and fungi. 11 − 13 …”

Section: Introductionmentioning

confidence: 99%

Highly Sensitive Surface-Enhanced Raman Spectroscopy Substrates of Ag@PAN Electrospinning Nanofibrous Membranes for Direct Detection of Bacteria

et al. 2020

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Surface-enhanced Raman spectroscopy (SERS) can be applied for biological detection because of its high sensitivity and noninvasiveness for analytes. Herein, we engineer plasmonic free-standing substrates composed of Ag nanoparticles (NPs) supported on polyacrylonitrile (PAN) electrospinning nanofibrous felts as sensors for bacterial detection. Ag NPs are evenly distributed on PAN nanofibers after preimpregnation and impregnation of PAN nanofibers in Tollens’ reagent. The size and loading density of Ag NPs are tunable by adjusting the reaction time of glucose and Tollens’ reagent, thereby allowing the tuning of the surface plasmon resonance. Using 4-mercaptophenol (4-MPh) and 4-mercaptobenzoic acid (4-MBA) as probe molecules, SERS effects of Ag@PAN composite nanofibers are investigated, and the substrates allow the detection of 4-MPh and 4-MBA at a low concentration of 10 –9 mol/L. Importantly, the substrates exhibit a high sensitivity of SERS performance for bacterial identification without a specific bacteria–aptamer conjugation. The SERS substrates also show good uniformity of SERS response for bacterial organelles. Furthermore, the antimicrobial property was evaluated, and the results indicate that the sample of Ag@PAN nanofiber mats possesses excellent antibacterial properties against Escherichia coli and Staphylococcus aureus .

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Section: Introductionmentioning

confidence: 99%

Highly Sensitive Surface-Enhanced Raman Spectroscopy Substrates of Ag@PAN Electrospinning Nanofibrous Membranes for Direct Detection of Bacteria

et al. 2020

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“…The results show that Au-Ag NSs-DTTC is an important and promising clinical antibacterial technology (Figure 15b-d). [148] Pearson et al compared the traditional aerobic plate counting (APC) and SERS sandwich methods based on the test results of the actual environment and food. The detection results of bacteria in pool water and spinach leaves showed that the SERS method could detect bacteria in fixed phase at a high level, with a sensitivity that was much higher than that of the APC method.…”

Section: Application Of Bacterial Detection In Clinical and Food Safetymentioning

confidence: 99%

Bacteria Detection: From Powerful SERS to Its Advanced Compatible Techniques

et al. 2020

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The rapid, highly sensitive, and accurate detection of bacteria is the focus of various fields, especially food safety and public health. Surface-enhanced Raman spectroscopy (SERS), with the advantages of being fast, sensitive, and nondestructive, can be used to directly obtain molecular fingerprint information, as well as for the on-line qualitative analysis of multicomponent samples. It has therefore become an effective technique for bacterial detection. Within this progress report, advances in the detection of bacteria using SERS and other compatible techniques are discussed in order to summarize its development in recent years. First, the enhancement principle and mechanism of SERS technology are briefly overviewed. The second part is devoted to a label-free strategy for the detection of bacterial cells and bacterial metabolites. In this section, important considerations that must be made to improve bacterial SERS signals are discussed. Then, the label-based SERS strategy involves the design strategy of SERS tags, the immunomagnetic separation of SERS tags, and the capture of bacteria from solution and dye-labeled SERS primers. In the third part, several novel SERS compatible technologies and applications in clinical and food safety are introduced. In the final part, the results achieved are summarized and future perspectives are proposed.

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“…Quantum dots have the advantages of size and special optical properties over traditional SERS‐active nanoparticles (Quagliano, 2004). Moreover, hybrid nanomaterials, such as gold‐silver nanoshells and graphene oxide‐wrapped gold nanorods, exhibit higher SERS enhanced capability than pure materials, which is attributed to their synergistic contribution to SERS (He et al, 2020; X. Qiu et al, 2017).…”

Section: Sers Nanoparticlesmentioning

confidence: 99%

Recent advances in applications of nanoparticles in SERS in vivo imaging

et al. 2020

WIREs Nanomed Nanobiotechnol

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Surface‐enhanced Raman scattering (SERS) technique has been regarded as one of the most important research methods in the field of single‐molecule science. Since the previous decade, the application of nanoparticles for in vivo SERS imaging becomes the focus of research. To enhance the performance of SERS imaging, researchers have developed several SERS nanotags such as gold nanostars, copper‐based nanomaterials, semiconducting quantum dots, and so on. The development of Raman equipment is also necessary owing to the current limitations. This review describes the recent advances of SERS nanoparticles and their applications for in vivo imaging in detail. Specific examples highlighting the in vivo cancer imaging and treatment application of SERS nanoparticles. A perspective on the challenges and opportunities of nanoparticles in SERS in vivo imaging is also provided. This article is categorized under: Diagnostic Tools > in vivo Nanodiagnostics and Imaging Therapeutic Approaches and Drug Discovery > Nanomedicine for Oncologic Disease

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Gold–silver nanoshells promote wound healing from drug-resistant bacteria infection and enable monitoring via surface-enhanced Raman scattering imaging

Cited by 120 publications

References 48 publications

Highly Sensitive Surface-Enhanced Raman Spectroscopy Substrates of Ag@PAN Electrospinning Nanofibrous Membranes for Direct Detection of Bacteria

Highly Sensitive Surface-Enhanced Raman Spectroscopy Substrates of Ag@PAN Electrospinning Nanofibrous Membranes for Direct Detection of Bacteria

Bacteria Detection: From Powerful SERS to Its Advanced Compatible Techniques

Recent advances in applications of nanoparticles in SERS in vivo imaging

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