Gonococcal oro- and nasopharyngeal infection.

Stolz, E.; Schüller, J.

doi:10.1136/sti.50.2.104

Cited by 18 publications

(10 citation statements)

References 20 publications

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“…had acute febrile tonsilitis (Bro-J0rgensen and Jensen, 1973). Similar results have been obtained by other investigators (Stolz and Schuller, 1974).…”

supporting

confidence: 85%

Radioimmunoassay for quantifying antibody to N. Gonorrhoeae in human sera.

Luoma¹,

Cross²,

Rudbach³

1975

Sexually Transmitted Infections

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“…had acute febrile tonsilitis (Bro-J0rgensen and Jensen, 1973). Similar results have been obtained by other investigators (Stolz and Schuller, 1974).…”

supporting

confidence: 85%

Radioimmunoassay for quantifying antibody to N. Gonorrhoeae in human sera.

Luoma¹,

Cross²,

Rudbach³

1975

Sexually Transmitted Infections

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“…As a result of our favourable situation, we had no problems in treating the patients with genital infections in whom the cure rate was 98 per cent. However, as reported by other authors (Bro-J0rgensen and Jensen, 1973;Odegaard and Gundersen, 1973;Stolz and Schuller, 1974), standard treatment was unsuccessful in pharyngeal infections in which the failure rate was 61 per cent. Promising results were obtained with high doses of penicillin intramuscularly for 2 days.…”

Section: Discussionmentioning

confidence: 67%

Gonorrhoea in 1972. A 1-year study of patients attending the VD Unit in Uppsala.

Wallin¹

1975

Sexually Transmitted Infections

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During 1972 all patients visiting the Venereal Disease Clinic of the University Hospital in Uppsala were subjected to careful and extensive interrogation, and the information so obtained was adapted for computer reading, as were the results of clinical examination and microbiological tests. The aim of this programme was not only to evaluate the adequacy of current therapy and epidemiological efforts, but also to illnte problems concerned with information and attitudes. The diagnosis of gonorrhoea was made if either a smear or a culture was positive for gonococci. Smears were considered positive if there was a collection of monomorphic diplococci within a neutrophilic granulocyte stained with methylene blue. Specimens from men were taken from the urethra and in a few cases also from the rectum, and in women from the urethra, cervix, and rectum. The material was transported in Stuart's medium to the laboratory and the culture set up within a few hours. Tonsillar swabs were taken from patients with an untreated gonococcal infection and from patients named as contacts. These were also sent to the laboratory in Stuart's medium and positive cultures from this site were confirmed with fermentation reactions. Methods PATIENTS TREATMENT SCHEDULES FOR GONORRHOEAThe standard treatment was a total of 2 g. ampicillin taken orally as two doses of 1 g. with a 5-hr interval. This treatment was given to 84 per cent. of the patients and the others were treated with either doxycycline, 300 mg. in a single oral dose, or 1 m.u. aqueous benzyl penicillin plus 1 2 m.u. aqueous procaine penicillin in a single injection. The efficacy of the therapy was checked by culture for N. gonorrhoeae of specimens taken one and two weeks after treatment.

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“…Gonococci isolated from the pharynx and from a second site in the same patient usually have identical antibiotic sensitivities (Bro-J0rgensen and Jensen, 1973;Stolz and Schuller, 1974;Hallqvist and Lindgren, 1975;Catlin and Pace, 1977a). However, pharyngeal isolates have been reported to be more resistant to ampicillin and penicillin (Odegaard and Gundersen, 1973;Hallqvist and Lindgren, 1975;Catlin and Pace, 1977b) and to have different auxotypes (Catlin and Pace, 1977b) when compared with genital isolates from other patients.…”

Section: Discussionmentioning

confidence: 99%

Pharyngeal colonisation by Neisseria gonorrhoeae and Neisseria meningitidis in black and white patients attending a venereal disease clinic.

Noble¹,

Cooper²,

Miller³

1979

Sexually Transmitted Infections

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SUMMARY Pharyngeal colonisation by Neisseria gonorrhoeae and Neisseria meningitidis was studied in 2000 patients attending a venereal disease clinic. Of these patients, 64 % were white and 36% were black. The incidence of gonococcal infections was highest in the period from June to August. The incidence of genital or rectal infections or both was higher in the black patients. Pharyngeal colonisation by gonococci was present in 1 3 % of the patients. There were no significant associations between pharyngeal colonisation and the pharyngeal symptoms, race, sex, or marital state of the patients. Pharyngeal colonisation was more frequent in patients with gonococcal infections at other sites. However, in 40 7 % of the patients with pharyngeal colonisation, the pharynx was the only culture-positive site. There was no significant difference in the auxotypes or in the antibiotic susceptibility of the pharyngeal and the rectal-genital isolates except in the susceptibility to spectinomycin. Our findings do not indicate that gonococci isolated from the pharynx differ significantly from gonococci isolated from rectal or genital sites. It was notable that meningococcal colonisation of the pharynx was significantly more frequent in the white patients. This may be a genetically determined phenomenon.

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Gonococcal oro- and nasopharyngeal infection.

Cited by 18 publications

References 20 publications

Radioimmunoassay for quantifying antibody to N. Gonorrhoeae in human sera.

Radioimmunoassay for quantifying antibody to N. Gonorrhoeae in human sera.

Gonorrhoea in 1972. A 1-year study of patients attending the VD Unit in Uppsala.

Pharyngeal colonisation by Neisseria gonorrhoeae and Neisseria meningitidis in black and white patients attending a venereal disease clinic.

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