Gordonia: isolation and identification in clinical samples and role in biotechnology

Andalibi, Fatemeh; Bafghi, Mehdi Fatahi

doi:10.1007/s12223-017-0491-1

Cited by 26 publications

(26 citation statements)

References 63 publications

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“…More and more people are turning to cyberspace to seek specific social support in various domains like coping with daily hassles and battling a life-threatening illness [16]. Social network sites like Twitter [17], Facebook [18], Instagram [19] or online forums [20][21][22] increase the opportunities of receiving and providing social support from all sides. Retransmission, or the so-called retweeting, has always been seen as a crucial indicator of information diffusion in social media platforms [23].…”

Section: Retransmission Of Help-seeking Posts and Content Characterismentioning

confidence: 99%

What triggers online help-seeking retransmission during the COVID-19 period? Empirical evidence from Chinese social media

Luo

Chen

et al. 2020

PLoS ONE

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The past nine months witnessed COVID-19's fast-spreading at the global level. Limited by medical resources shortage and uneven facilities distribution, online help-seeking becomes an essential approach to cope with public health emergencies for many ordinaries. This study explores the driving forces behind the retransmission of online help-seeking posts. We built an analytical framework that emphasized content characteristics, including information completeness, proximity, support seeking type, disease severity, and emotion of helpseeking messages. A quantitative content analysis was conducted with a probability sample consisting of 727 posts. The results illustrate the importance of individual information completeness, high proximity, instrumental support seeking. This study also demonstrates slight inconformity with the severity principle but stresses the power of anger in help-seeking messages dissemination. As one of the first online help-seeking diffusion analyses in the COVID-19 period, our research provides a reference for constructing compelling and effective help-seeking posts during a particular period. It also reveals further possibilities for harnessing social media's power to promote reciprocal and cooperative actions as a response to this deepening global concern.

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Section: Retransmission Of Help-seeking Posts and Content Characterismentioning

confidence: 99%

What triggers online help-seeking retransmission during the COVID-19 period? Empirical evidence from Chinese social media

Luo

Chen

et al. 2020

PLoS ONE

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“…Some Gordonia species cause a broad spectrum of diseases in healthy and immunocompromised individuals. Besides, these bacteria can produce useful secondary metabolites that may be used in various industries [26].…”

Section: Discussionmentioning

confidence: 99%

Antimicrobial compounds were isolated from the secondary metabolites of endophytic Gordonia in the intestinal tract of Periplaneta americana

Liu

et al. 2021

Preprint

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Background: As we all know, bacterial and fungal infections have become one of the threats to human health. Microbial secondary metabolites are one of the main sources of bioactive natural products. It is estimated that around 60% of all foregone antibiotics are derived from secondary metabolites produced by filamentous actinomycete bacteria. Gordonia spp. are members of the actinomycete family, their contribution to the environment improvement and environmental protection by their biological degradation ability, but there are few studies on their antimicrobial activity of their secondary metabolites. Our team isolated a Gordonia strain WA 4-31 with anti-Candida albicans activity from the intestinal tract of Periplaneta americana in the early stage.Results: In this study, we firstly identified the strain WA 4-31 by the morphological characteristics and the phylogenetic analyses, and found that it homologous to a strain of Gordonia from the Indian desert (EU333873) by 100%. Then four compounds, Actinomycin D (1), Actinomycin X2 (2), Mojavensin A (3) and cyclic (leucine-leucne) dipeptide (4) were purified from the EtOH extract of the fermented broth of the strain. The compounds 1-4 had activities against Candida albicans, Aspergillus niger, Aspergillus fumigatus and Trichophyton rubrum. They also had activities against MRSA, S.aureus, K.peneumoniae and E.coli in different degree. The minimum inhibitory concentration of Actinomycin D and Actinomycin X2 on MASA was 0.25 μg/mL. Interestingly, we found that when Mojavensin A was mixed with compound 4 ratio of 1:1, the solution of the compounds was better than the single on anti-Candida albicans. Besides, compounds 1-3 had varying degrees of cytotoxicity on CNE-2 cells and HepG-2 cells.Conclusions: The present study firstly reported the antimicrobial compounds isolated from Gordonia. These indicated that rare actinomycetes from the intestinal tract of Periplaneta americana possessed a potential as a source of active secondary metabolites.

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“…Gordonia species do not generate spores 1 . Some of these microorganisms were initially classified as rhodococci, and Gordonia species are rarely reported as causative agents of diseases in humans 2 , 3 . Understanding of their medical significance and pathogenicity among the community of medical and veterinary professionals is still limited.…”

Section: Introductionmentioning

confidence: 99%

Gordonia species as a rare pathogen isolated from milk of dairy cows with mastitis

Bzdil¹,

Šlosárková

Fleischer

et al. 2022

Sci Rep

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While Gordonia species have long been known to cause severe inflammation in humans, the pathogenic effects of Gordonia species in veterinary medicine have rarely been described. Between 2010 and 2019, we collected microorganisms of the genus Gordonia isolated from milk samples from dairy cows with mastitis. We describe the growth properties of these microorganisms and their prevalence, virulence factors and susceptibility to antimicrobial agents. From 31,534 quarter milk samples processed by standard culture methods, 27 isolates of Gordonia species (0.086% prevalence) were identified by a molecular phenotyping method. The isolates originated from 17 farms in 12 districts of the Czech Republic. Twenty-one isolates were tested for susceptibility to 7 antimicrobials by the disc diffusion method. Notably, 100% of these isolates were susceptible to streptomycin and neomycin, 85.7% to cefovecin and tetracycline, 76.2% to penicillin G, 47.6% to trimethoprim/sulfamethoxazole and 0% to clindamycin. The species was determined to be Gordonia paraffinivorans by whole genome sequencing for 9 isolates (from 8 farms in 7 districts). These isolates showed the highest similarity to two reference strains from the environment. In all these isolates, we identified genes encoding virulence factors that are very similar to genes encoding virulence factors expressed in Mycobacterium tuberculosis and Mycobacterium smegmatis. However, genome analysis revealed 61 unique genes in all 9 sequenced isolates.

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Gordonia: isolation and identification in clinical samples and role in biotechnology

Cited by 26 publications

References 63 publications

What triggers online help-seeking retransmission during the COVID-19 period? Empirical evidence from Chinese social media

What triggers online help-seeking retransmission during the COVID-19 period? Empirical evidence from Chinese social media

Antimicrobial compounds were isolated from the secondary metabolites of endophytic Gordonia in the intestinal tract of Periplaneta americana

Gordonia species as a rare pathogen isolated from milk of dairy cows with mastitis

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