Governance of wastewater surveillance systems to minimize the impact of COVID-19 and future epidemics:Cases across Asia-Pacific

Takeda, Tomoko; Kitajima, Masaaki; Abeynayaka, Amila; Huong, Ngo Thi Thanh; Dinh, N. Q.; Sirikanchana, Kwanrawee; Navia, M.; Sam, Afshin; Tsudaka, Masashi; Setiadi, Tjandra; Hung, D. T.; Haramoto, Eiji

doi:10.1016/b978-0-323-85512-9.00010-3

Cited by 6 publications

(6 citation statements)

References 12 publications

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“…The next-generation sequencingbased method Swab-Seq is another technique utilizing RT-PCR primers, which has exclusive molecular codes for the sequencing of many samples (Bloom et al, 2020). Decentralized wastewater samples are quite difficult to manage due to the rigorous sample collection process for households (Takeda et al, 2021). Analysis of the high-risk points is needed as a solution to this problem, which includes quarantine areas, hospitals, and healthcare services.…”

Section: Limitations In Wastewater Surveillancementioning

confidence: 99%

“…Sample analysis would require equipment for the health and research sectors involving national and international platforms for wastewater surveillance (UN Women, 2020). Budgets should be established for prevention and response, along with the establishment of committees to meet regional and international goals (Takeda et al, 2021). The calibration of viral RNA needs to be performed against the exact number of cases presented by marking and targeting biomarkers (Daughton, 2020).…”

Section: Limitations In Wastewater Surveillancementioning

confidence: 99%

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COVID-19 surveillance in wastewater: An epidemiological tool for the monitoring of SARS-CoV-2

Maryam

Haq

Yahya

et al. 2023

Front. Cell. Infect. Microbiol.

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The coronavirus disease 2019 (COVID-19) pandemic has prompted a lot of questions globally regarding the range of information about the virus’s possible routes of transmission, diagnostics, and therapeutic tools. Worldwide studies have pointed out the importance of monitoring and early surveillance techniques based on the identification of viral RNA in wastewater. These studies indicated the presence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in human feces, which is shed via excreta including mucus, feces, saliva, and sputum. Subsequently, they get dumped into wastewater, and their presence in wastewater provides a possibility of using it as a tool to help prevent and eradicate the virus. Its monitoring is still done in many regions worldwide and serves as an early “warning signal”; however, a lot of limitations of wastewater surveillance have also been identified.

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Section: Limitations In Wastewater Surveillancementioning

confidence: 99%

Section: Limitations In Wastewater Surveillancementioning

confidence: 99%

COVID-19 surveillance in wastewater: An epidemiological tool for the monitoring of SARS-CoV-2

Maryam

Haq

Yahya

et al. 2023

Front. Cell. Infect. Microbiol.

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“…It has also been used as a valuable instrument to provide information about the emergence and abundance of SARS-CoV-2 strains (Nemudryi et al 2020;Rimoldi et al 2020;Crits-Christoph et al 2021;Jahn et al 2021). Many countries have already implemented a national wastewater surveillance system or program to support the government in formulating epidemic prevention policies for COVID-19, including the Netherlands (Rijksoverheid 2021), the USA (CDC 2021; Kirby et al 2021), the UK (Wade et al 2022), South Africa (NICD 2021), Japan (Takeda et al 2021) and others.…”

Section: Introductionmentioning

confidence: 99%

One-year surveillance of SARS-CoV-2 in wastewater from vulnerable urban communities in metropolitan São Paulo, Brazil

Barbosa

Garcia

Bruni

et al. 2022

Journal of Water and Health

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The current COVID-19 pandemic has emphasized the vulnerability of communities living in the urban outskirts and informal settlements. The lack of reliable COVID-19 case data highlights the importance and application of wastewater-based epidemiology. This study aimed to monitor the COVID-19 trends in four vulnerable urban communities (slums and low-income neighborhoods) in metropolitan São Paulo by assessing the SARS-CoV-2 RNA viral load in wastewater. We analyzed 160 samples from May 2020 to June 2021 with weekly or fortnightly samplings. The samples were ultracentrifuged with glycine elution and quantified by N1/N2 SARS-CoV-2 RT-qPCR. The results of positivity were 100% (Paraisópolis, Heliópolis and Cidade Tiradentes) and 76.9% (Vila Brasilândia). The new case numbers of COVID-19, counted from the onset of symptoms, positively correlated with SARS-CoV-2 N1 viral loads from the two largest communities (p<0.001). SARS-CoV-2 infectivity was tested in Vero E6 cells after concentration with the two techniques, ultrafiltration (Centricon® Plus-70 10 kDa) and sucrose cushion ultracentrifugation, but none of the evaluated samples presented positive results. Next-generation sequencing (NGS) analysis from samples collected in March and August 2021 revealed the presence of the clade 20 J (lineage P.1) belonging to the most prevalent circulating variant in the country. Our results showed that wastewater surveillance data can be used as complementary indicators to monitor the dynamics and temporal trends of COVID-19. The infectivity test results strengthened the evidence of low risk of infection associated with SARS-CoV-2 in wastewater.

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“…Local governments in all nations are in charge of the actual implementation and operation of wastewater treatment and monitoring facilities. Academic/research organizations and the corporate sector are primarily responsible for sample analysis and the creation of technical solutions, including monitoring equipment [ 12 ]. PCRWR's microbiological testing kit and arsenic testing kit for pathogenic and chemical surveillance are examples of such equipment [ 11 ].…”

mentioning

confidence: 99%

“…As a result, while developing a national platform for wastewater surveillance systems, it is necessary to include all authorities [ 12 ]. The government should ensure that the governance structure for wastewater surveillance systems is not only a stopgap solution, but rather serves as an early warning system for future pandemics.…”

mentioning

confidence: 99%

Wastewater surveillance in Pakistan: Preventing future epidemics

Bilal

Vohra

Sahito

et al. 2022

Annals of Medicine &Amp; Surgery

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Governance of wastewater surveillance systems to minimize the impact of COVID-19 and future epidemics:Cases across Asia-Pacific

Cited by 6 publications

References 12 publications

COVID-19 surveillance in wastewater: An epidemiological tool for the monitoring of SARS-CoV-2

COVID-19 surveillance in wastewater: An epidemiological tool for the monitoring of SARS-CoV-2

One-year surveillance of SARS-CoV-2 in wastewater from vulnerable urban communities in metropolitan São Paulo, Brazil

Wastewater surveillance in Pakistan: Preventing future epidemics

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