Grading of Ultrasonography in Rheumatoid Arthritis of Wrist and Hand Joints

Seifeldein, Gehan S.; Moussa, Doaa Kabil; Galal, Marwa A.A.; Othman, Mostafa; El-Malah, Hosam EldeinGalal Mohamed

doi:10.1016/j.acra.2019.09.033

Cited by 4 publications

(2 citation statements)

References 27 publications

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“…In contrast, PDUS is a useful US method to confirm active synovitis in target joints. In this context, many studies including the current study have demonstrated that the sum of the PDUS grades correlate with serum inflammatory markers and SJC in patients with RA [33,42,43]. However, the Sum of PDUS grade did not correlate with TJC in patients with RA in this study.…”

Section: Discussioncontrasting

confidence: 73%

“…The Sum of PD grade correlated better with serum inflammatory markers (ESR and CRP) and assessments of patient global health (VAS-GH). All three previous studies that evaluated the correlations between MSUS parameters and clinical disease activity markers have shown that the sums of the PDUS or GSUS semi-quantitative grades correlated well with DAS28 in patients with established RA [33,42,43] and patients with EIA [19]. However, the sums of the GSUS grades did not exhibit significant correlations with DAS28, unlike the sums of the PDUS grades, in a study of 50 RA patients reported by El-Gohary et al [33].…”

Section: Discussionmentioning

confidence: 78%

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A Pragmatic Application of Ultrasonography for the Assessment of Disease Activity in Patients with Early Inflammatory Arthritis

Nam

Kang²

2021

JCM

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The aim of the study was to examine the usefulness of targeted musculoskeletal ultrasonography (MSUS) in assessing the disease activity of patients with early inflammatory arthritis (EIA). Twenty-eight patients with EIA were enrolled. The MSUS examination of joints with arthritic signs (tenderness or swelling), measurement of 28-joint Disease Activity Score (DAS28), and its components were performed at four-week interval visits until power doppler (PD) US remission was achieved. Various MSUS parameters of grey scale (GS) and PD synovitis were measured. Pearson or Spearman correlation coefficients were determined for the purpose of the study. Data were gathered from a total of 85 visits. The Sum of GS grade correlated better with physical examination findings, while the Sum of PD grade correlated better with serum inflammatory markers and patient global health. However, Global OMERACT-EULAR Synovitis Score (GLOESS), which reflected both PD and GS grades, correlated evenly well with each clinical parameter. In addition, GLOESS correlated best with DAS28 in the overall study population (p < 0.01). Conclusively, our targeted MSUS parameters of arthritic joints, especially sums of semi-quantitative grades of synovitis, could be useful in monitoring patients with EIA.

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Section: Discussioncontrasting

confidence: 73%