Granular Cell Nerve Tumor in the Hand: Case Report

Slutsky, David J.

doi:10.1016/j.jhsa.2009.05.011

Cited by 8 publications

(11 citation statements)

References 10 publications

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“…The differential diagnosis for these extremely rare nerve tumours includes the more common neurofibroma and schwannoma, which cannot be differentiated on clinical grounds or by imaging. [1]…”

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confidence: 99%

“…Only 1-3% of all reported cases are malignant. [3] Even though the true recurrence rate following resection is unknown, wide resection of the tumour when it occurs in a digital nerve is recommended by Slutsky [1] based on its propensity for local recurrence. The use of radiotherapy and chemotherapy is advisable only in treating the malignant forms of such tumours.…”

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confidence: 99%

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Granular cell tumour of the hand

Korambayil¹

2012

Indian J Plast Surg

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confidence: 99%

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confidence: 99%

Granular cell tumour of the hand

Korambayil¹

2012

Indian J Plast Surg

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“…It can also been found in the soft tissue, nerve, breast, scalp, abdominal wall, head and neck, back, extremities, lymphnode, mediastinum, soft palate, orbit, salivary glands, respiratory tract, vulva, gastrointestinal tract, brain. [1–91113] GCT commonly presents as an asymptomatic slow growing, solitary, painless nodule that may have either smooth or hyperkeratotic overlying skin. [3–6] The lesions are usually less than 3.0 cm in size and may undergo partial regression.…”

Section: Discussionmentioning

confidence: 99%

“…[4] Wide en bloc excision is recommended for malignant lesions. [391213] Chemotherapy, alone or in association with radiotherapy, is not given unless the tumor is malignant. [3]…”

Section: Discussionmentioning

confidence: 99%

Granular cell tumor of hand presenting as subcutaneous nodule mimicking dermal adnexal tumor: A diagnosis by cytology

Nasit

Chauhan

Dhruva

2013

Indian Dermatol Online J

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Granular cell tumor (GCT) is an uncommon tumor and is believed to be of schwannian origin. GCT is benign but rare malignant cases are recorded. GCT occurs in almost any part of the body. The common sites are the tongue, skin, and subcutaneous tissue. GCT of hand is an extremely rare. Till date only 17 cases are reported in the literature. Preoperative diagnosis of GCT is important, because GCT mimics dermal adnexal tumor in subcutaneous tissue, other soft tissue tumor or inflammatory lesions. GCT is composed of large polygonal cells with eosinophilic granular cytoplasm and these cells are often immunoreactive for the S-100 protein. Fine-needle aspiration cytology has been suggested to be diagnostic modality of choice and this would undoubtedly aid the correct diagnosis. Excision with wide surgical margins is curative for benign GCT. Recurrence and malignant transformation requires regular follow-up. Here, this communication documents a case of cytological diagnosis of the granular cell tumor of hand in a 21-year-old female, clinically suspected to be a dermal adnexal tumor.

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“…Granular cell tumor (GCT) is a rare soft tissue neoplasm of presumed neuroectodermal origin [1,2]. The majority are benign, and a malignant variant accounts for only 1-3% of cases [3,4].…”

Section: Introductionmentioning

confidence: 99%

Granular cell tumor of the hand: A case report

Fanto¹,

Fanto²

2014

IJCRI

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International Journal of Case Reports and Images (IJCRI) is an international, peer reviewed, monthly, open access, online journal, publishing high-quality, articles in all areas of basic medical sciences and clinical specialties.Aim of IJCRI is to encourage the publication of new information by providing a platform for reporting of unique, unusual and rare cases which enhance understanding of disease process, its diagnosis, management and clinico-pathologic correlations. The lesions tend to be small and solitary, asymptomatic, and typically found in the dermis or subcutaneous tissue. They have rarely been reported as occurring in the hand. Complete excision is usually curative. However, malignant tumors have been reported, which may metastasize. Case Report: We report a case of a granular cell tumor of the hand. Conclusion: This case is of particular interest due to the atypical location, and clinical presentation, which despite its malignant potential, mimics that of more commonly encountered benign lesions such as ganglion cysts and inclusion cysts.

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Granular Cell Nerve Tumor in the Hand: Case Report

Cited by 8 publications

References 10 publications

Granular cell tumour of the hand

Granular cell tumour of the hand

Granular cell tumor of hand presenting as subcutaneous nodule mimicking dermal adnexal tumor: A diagnosis by cytology

Granular cell tumor of the hand: A case report

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