Granulomas of the membranous vocal fold after intubation and other airway instrumentation

Sadoughi, Babak; Rickert, Scott; Sulica, Lucian

doi:10.1002/lary.27492

Cited by 13 publications

(20 citation statements)

References 12 publications

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“…Other etiologies of diffuse laryngeal erythema include traumatic injury from intubation, vocal abuse, and gastroesophageal reflux disease. 15,16 This case represents a unique etiology of laryngotracheal granulomatous disease, and an unusual presentation of sporotrichosis. While respiratory tract sporotrichosis has been described previously, laryngeal involvement is rare.…”

Section: Discussionmentioning

confidence: 96%

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Chronic Laryngotracheal Granulomatous Disease Secondary to Sporothrix schenckii in an Immunocompromised Patient

Kenny

Dougherty

Churnin

et al. 2022

Ann Otol Rhinol Laryngol

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Objective: To describe a rare presentation of laryngotracheal granulomatous disease secondary to sporotrichosis. Methods: The authors report a case of laryngeal sporotrichosis in an immunocompromised patient, with accompanying endoscopic images and pathology. Results/case: A 72-year-old immunocompromised female with a history of rose-handling presented with a year of hoarseness and breathy voice. Flexible nasolaryngoscopy showed diffuse nodularity; biopsy of the lesions demonstrated granulomatous inflammatory changes, and fungal culture grew Sporothrix schenkii. Long-term itraconazole treatment was initiated, with improvement in dysphonia and few residual granulomas on follow-up examination. Conclusion: When evaluating granulomatous disease of the airway, a broad differential including infectious or inflammatory etiologies should be considered, especially in immunocompromised patients. Adequate tissue samples should be collected to facilitate special staining. The current recommendations for laryngeal sporotrichosis include treatment with a prolonged course of itraconazole.

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Section: Discussionmentioning

confidence: 96%

“…Other etiologies of diffuse laryngeal erythema include traumatic injury from intubation, vocal abuse, and gastroesophageal reflux disease. 15,16…”

Section: Discussionmentioning

confidence: 99%

Chronic Laryngotracheal Granulomatous Disease Secondary to Sporothrix schenckii in an Immunocompromised Patient

Kenny

Dougherty

Churnin

et al. 2022

Ann Otol Rhinol Laryngol

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“…7 On the contrary, this might also cause false diagnoses of LPRD, which showed that the use of empirical PPI therapy did not lead to any improvement in persistent throat symptoms in 16 weeks or 12 months. 33 (2) An insufficient awareness about related diseases could cause poor efficacies or recurrences in treating such diseases, as antireflux therapy has been accepted in treating some of these diseases, such as laryngeal leukoplakia, 34 laryngeal granuloma 35 and cough. 36 (3) Currently, no perfect diagnostic and treatment methods exist for LPRD: simple ones are not so accurate or effective, such as RSI or RFS evaluations (diagnosis) and behavioural changes (treatment), while accurate or effective ones are always invasive, such as pH-MII monitoring (diagnosis) or antireflux operations (treatment).…”

Section: Open Accessmentioning

confidence: 99%

Awareness about laryngopharyngeal reflux disease among Chinese otolaryngologists: a nationwide survey

Xiao

Zheng

et al. 2022

BMJ Open

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ObjectivesThis study aimed to investigate the status of the current knowledge about laryngopharyngeal reflux disease (LPRD) among Chinese otolaryngologists.DesignMulti-centre cross-sectional survey.Setting220 medical centres in different regions of China.ParticipantsA total of 2254 otolaryngologists from 220 medical centres in China who were successfully on-site surveyed between November 2019 and December 2020.Main outcome measuresAwareness about LPRD included knowledge about risk factors, symptoms, laryngoscope signs, related diseases, current diagnostic methods and treatments.ResultsThe percentage of participants who had heard of LPRD was 96.4%, with academic conferences as the most common source of information (73.3%). The most commonly known risk factor, symptom, laryngoscope sign, related disease, diagnostic method and treatment were alcohol consumption (44.0%), pharyngeal foreign body sensation (66.9%), hyperaemia (52.4%), pharyngolaryngitis (54.8%), pH monitoring (47.6%) and medication (82.1%), respectively. Only 28.3% of all participants knew that 24 h pH or multichannel intraluminal impedance pH monitoring was the most accurate diagnostic test. As many as 73.1% of all participants knew that proton pump inhibitors were the first-line treatment drugs. An analysis of the overall status of awareness using a scoring system suggested that otolaryngologists were better aware owing to more access, working at 3A hospitals, and postgraduate or above educational background (all p<0.05).ConclusionAlthough the majority of Chinese otolaryngologists had heard of LPRD, their overall awareness about the disease was not encouraging. More efforts are needed to increase the knowledge about LPRD among this group of physicians.Trial registration numberChiCTR1900025581

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“…The authors passed an adult fiberoptic scope from the other nostril and then by the side of the ETT to enter the trachea. They succeeded but this can lead to a theoretical trauma to the vocal cord or membranous granuloma of the vocal cord[ 2 ] and/or prolonged hoarseness in postoperative period. In our view a proper preoperative planning of airway is required to avoid such unwanted intraoperative interventions.…”

mentioning

confidence: 99%

Comment on “changing nasal endotracheal tube to opposite nostril in a patient with no mouth opening under general anesthesia, after initial awake fiberoptic intubation

Solanki

Doctor

2021

Saudi Journal of Anaesthesia

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Granulomas of the membranous vocal fold after intubation and other airway instrumentation

Abstract: 4 Laryngoscope, 2018.

Cited by 13 publications

References 12 publications

Chronic Laryngotracheal Granulomatous Disease Secondary to Sporothrix schenckii in an Immunocompromised Patient

Chronic Laryngotracheal Granulomatous Disease Secondary to Sporothrix schenckii in an Immunocompromised Patient

Awareness about laryngopharyngeal reflux disease among Chinese otolaryngologists: a nationwide survey

Comment on “changing nasal endotracheal tube to opposite nostril in a patient with no mouth opening under general anesthesia, after initial awake fiberoptic intubation

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