Granulomatous Diseases of the Central Nervous System

Rocha, Antônio José da; Maia, Antônio Carlos Martins; Ferreira, Nelson P.; Amaral, Lázaro Luís Faria do

doi:10.1097/01.rmr.0000189109.62899.a1

Cited by 37 publications

(28 citation statements)

References 89 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Although DeLone et al. [23] described a frequency of callosal lesions in seven of 18 patients in his cohort, callosal lesions are not typical of aspergillosis, but more common than in other infections including toxoplasmosis [24]. Pyogenic infection and thrombotic infarction do not commonly involve the corpus callosum [23].…”

Section: Discussionmentioning

confidence: 99%

Relevant imaging findings of cerebral aspergillosis on MRI: a retrospective case‐based study in immunocompromised patients

Gabelmann

Klein

Kern

et al. 2007

Euro J of Neurology

View full text Add to dashboard Cite

The aim of the study was to assess neuroimaging patterns of cerebral aspergillosis with magnetic resonance imaging (1.5 T). The clinical and imaging data of nine patients were reviewed. Patients were included in the study if the diagnosis of aspergillosis was confirmed by either biopsy, autopsy, aspergillus antigen determination and/or neuroradiological and clinical response to specific treatment. Four patients had single or multiple abscesses presenting as ring-enhancing lesions on T1-weighted images, hypointensity of the ring on T2-weighted MR images and low to high signal intensity on diffusion-weighted imaging. Four patients had single or multiple infarctions affecting all compartments of the brain with hyperintensities on T2-weighted images in three of four patients, irregular parenchymal contrast enhancement in all patients and hemorrhagic transformation of the infarcted parenchyma in one patient. Diffusion-weighted images were positive in all ischemic areas. One patient with paranasal sinusitis developed a mycotic aneurysm of the internal carotid artery. Cerebral aspergillosis presents three principal neuroimaging findings: areas consistent with infarction; ring lesions consistent with abscess formation following infarction; and dural or vascular infiltration originating from paranasal sinusitis or orbital infiltration. Recognition of these patterns in cerebral aspergillosis may lead to more timely and effective diagnosis and treatment.

show abstract

Section: Discussionmentioning

confidence: 99%

Relevant imaging findings of cerebral aspergillosis on MRI: a retrospective case‐based study in immunocompromised patients

Gabelmann

Klein

Kern

et al. 2007

Euro J of Neurology

View full text Add to dashboard Cite

show abstract

“…MRI features depend on whether granulomas are caseous, as generally observed in mycobacterial infections, and whether the caseous matter has a solid (hypointense signal on T2, Fig. 1b and e) or liquefied (hyperintense signal on T2) center [2]. The hypointense signal observed on T2 results from solid caseation and associated fibrosis, gliosis and chronic inflammatory infiltration byproduct within these lesions (Supplementary data).…”

Section: Journal Of the Neurological Sciences J O U R N A L H O M E Pmentioning

confidence: 96%

Isolated intracranial Mycobacterium avium complex granulomas in an immune-competent man

Dubbioso

Cerillo

D’Arco

et al. 2015

Journal of the Neurological Sciences

View full text Add to dashboard Cite

“…CNS granulomas can be associated with infectious diseases, such as parasitic, bacterial and fungal granulomatous infections (1). Characteristic clinical features of CNS granulomatous infections include seizures, focal neurologic deficits and multiple 'nodular or ring' enhancing lesions on brain magnetic resonance imaging (MRI).…”

Section: Introductionmentioning

confidence: 99%

Disseminated Intracranial Tuberculoma Mimicking Neurocysticercosis

Zhang

Qiu

2011

Intern. Med.

View full text Add to dashboard Cite

Intracranial tuberculoma and neurocysticercosis (NCC) are the most frequent granulomatous infections in the central nervous system. Here we report a 41-year-old man with disseminated intracranial tuberculoma mimicking NCC. The patient complained of relapsing vertigo and vomiting consistent with Bruns syndrome. Serum antibodies against cysticercosis were positive. Magnetic resonance imaging (MRI) of the brain showed multiple disseminated ring-enhanced lesions. An initial diagnosis of NCC was made based on clinical signs and MRI. However, during antiparasitic treatment, the patient exhibited fever, meningitis signs, and positive cerebrospinal fluid findings for tuberculosis. The diagnosis was therefore corrected as tuberculoma. After three months of antituberculous treatment, the patient recovered clinically and on MRI. Our results highlight the importance of differential diagnosis of these two diseases in the early stage.

show abstract

Granulomatous Diseases of the Central Nervous System

Cited by 37 publications

References 89 publications

Relevant imaging findings of cerebral aspergillosis on MRI: a retrospective case‐based study in immunocompromised patients

Relevant imaging findings of cerebral aspergillosis on MRI: a retrospective case‐based study in immunocompromised patients

Isolated intracranial Mycobacterium avium complex granulomas in an immune-competent man

Disseminated Intracranial Tuberculoma Mimicking Neurocysticercosis

Contact Info

Product

Resources

About