“…Artifacts in mtMPS data from background noise, damage, and NUMTs will occur and can negatively impact interpretation, including the interpretation of heteroplasmy. ISFG and recent published studies have provided recommendations and guidelines for navigating the interpretation and reporting process of mtMPS data (Crysup et al, 2021; Kim et al, 2018; Marshall & Parson, 2021; Parson et al, 2014; Sukser et al, 2021; SWGDAM Guidelines, 2019).…”