Graphene-MoS2-Au-TiO2-SiO2 Hybrid SPR Biosensor: A New Window for Formalin Detection

Abstract

In this article, numerically a surface plasmon resonance (SPR) biosensor is developed based on Graphene-M­­­­OS2-Au-TiO2-SiO2 hybrid structure for formalin detection. This developed sensor sensed the presence of formalin by applying attenuated total reflection (ATR). In ATR method, we developed and observed two characteristics curve, one is “SPR angle versus minimum reflectance (Rmin)” and another is “SPR frequency (SPRF) versus maximum transmittance (Tmax). In the proposed sensor, Chitosan is used as probe legend to perform specific reaction with the formalin (40% formaldehyde) as target legend. Here, graphene and MoS2 both are used as biomolecular acknowledgment element (BAE). And TiO2 as well as SiO2 bilayers are used to improve sensor sensitivity and Gold (Au) is to sharp SPR curve. In numerical results, the variation of SPRF and SPR angle for inappropriate sensing of formalin is quiet insignificant which confirms the absence of formalin. On the other hand, these variations for appropriate sensing is considerably significant that confirms the presence of formalin. At the end of this article, a study of variation of sensitivity of the proposed biosensor in corresponding to the increment of refractive index with a refractive index step 0.01 RIU is measured. In inclusion of TiO2-SiO2 bilayers with Graphene-M­­­­OS2, maximum sensitivity of 85.375% more is numerically reported.

A Numerical Approach to Design the Kretschmann Configuration Based Refractive Index Graphene-MoS2 Hybrid Layers With TiO2-SiO2 Nano for Formalin Detection

“…For an inciting TM polarized light, a polarizer is used in the way of incident. For the angular interrogation method, the Kretschmann arrangement based sensor, this paper considers the Fresnel optical system to design the proposed sensor which was discussed in detail in [9][10][11][12][13][14][15][16]. To give extra momentum to the incident light, high wave vector photonic crystals need to be used [40].…”

“…In recent years, refractive index based surface plasmon resonance (SPR) bio-sensing has been widely researched because this sensor technology has a great potential for detection and analysis of chemical and biochemical substances in many important areas including medicine, biotechnology, monitoring of drug, food quality, environment safety, formalin detection, medical diagnosis, enzyme detection, and doxyribonucleic acid (DNA-DNA) hybridization [8][9][10][11][12][13][14][15][16][17][18][19].…”

“…Titanium dioxide (TiO 2 ) is one of the most widely used semiconductors in photo catalysis and solar energy conversion [22]. As an SPR sensitive material, it has distinguished advantages such as low cost, high stability, high permittivity, and environmental friendliness [16,18,36,37]. The silicon dioxide (SiO 2 ) layer also increases the sensitivity of the probe [16,18,38,39].…”

“…This effective light trapping generates more surface plasmons (SPs) which will eventually enhance the SPR angle and frequency. This rise of SPR angle and frequency will increase the sensor sensitivity [16,38].…”

Numerical Analysis and Design of Photonic Crystal Fiber Based Surface Plasmon Resonance Biosensor

“…92003 28 Journal of Sensor Technology from the other biosensors because of its high sensitivity and reliable procedure [8]. Kretschmann configuration [8] is widely used in which a very thin layer of metal is directly deposited on the surface of coupling prism. It is bulky in size and difficult to optimize.…”