2019
DOI: 10.1016/j.msec.2019.05.008
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Graphene/nickel oxide nanocomposites against isolated ESBL producing bacteria and A549 cancer cells

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Cited by 45 publications
(13 citation statements)
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References 81 publications
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“…6 a shows with smooth, tightly packed and clumped morphological colonies were observed. Our result was agreed by recent report of Rajivgandhi et al (2019b) and loss of red color intensity is refereed as notable reduction in mitochondrial membrane stability. Similarly, loss of mitochondrial membrane damage by destabilization and functional alteration leads to high mortality was most effective in treatment of cancer cells.…”
Section: Resultssupporting
confidence: 94%
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“…6 a shows with smooth, tightly packed and clumped morphological colonies were observed. Our result was agreed by recent report of Rajivgandhi et al (2019b) and loss of red color intensity is refereed as notable reduction in mitochondrial membrane stability. Similarly, loss of mitochondrial membrane damage by destabilization and functional alteration leads to high mortality was most effective in treatment of cancer cells.…”
Section: Resultssupporting
confidence: 94%
“…5 b). It was clearly confirmed that the ROS was generated intracellularly in A549 cells due to the Ag NPs influences ( Rajivgandhi et al, 2019b ). In addition, the continuous ROS production of the cells was gone to decline phase and leads to death due to the suppressed activator genes.…”
Section: Resultsmentioning
confidence: 76%
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“…As the complications related to side effects are increasing, a prodrug specific to the cancer cells can be designed that can be initiated by an enhanced level of ROS present in cancer cells, and it can minimize the risk of unwanted side effects [273]. Similarly, the production of ROS can be targeted to develop a combinatorial treatment method of nanoparticles with anticancer drugs, which can provide a nanoparticle-based redox-directed combinational anticancer therapy to treat cancer [274]. Besides the conventional treatment methods, the alternative medicines are gaining popularity because of their lower possibility of causing treatment-related complications.…”
Section: Future Perspectivementioning
confidence: 99%
“…NiO nanocomposites have cytotoxic effect. These substances were found to increase the level of ROS, reduce cell viability, and modify cell cycle arrest (38). Antirheumatic agents, also known as "Disease-Modifying Anti-Rheumatic Drugs" (DMARDs), include methotrexate, hydroxychloroquine, sulfasalazine, penicillamine, azathioprine, and the thiopurines.…”
Section: Chemicals Related To Lung Squamous Cell Carcinoma By Gseamentioning
confidence: 99%