Graphitic carbon nitride-based nanoplatforms for biosensors: design strategies and applications

Gupta, Nidhi Rani; Todi, Keshav; Narayan, Tarun; Malhotra, Bansi D.

doi:10.1016/j.mtchem.2021.100770

Cited by 26 publications

(12 citation statements)

References 177 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…2.5.2.1 Hard templates. Hard templates like porous anodic metal oxide (i.e., alumina oxide (AAO) and ZnO) 82,112,113 and silica (i.e., SBA-15, SBA-16, FDU-12, and KIT-6) [114][115][116] are exhaustively used for the preparation of porous g-C 3 N 4 with different structures (i.e., nanotubes, nanorods, and nanospheres). This followed pioneering work done by Goettmann et al 117 who mixed cyanamide with 12 nm SiO 2 particles in water, which was heated to 550 °C for 2h and then 4 h, followed by immersion in NH 4 HF 2 for two days to remove the silica template.…”

Section: Green Methods For the Synthesis Of G-c 3 N 4 -Based Catalystsmentioning

confidence: 99%

See 1 more Smart Citation

Graphitic carbon nitride-based nanostructures as emergent catalysts for carbon monoxide (CO) oxidation

2023

View full text Add to dashboard Cite

show abstract

Section: Green Methods For the Synthesis Of G-c 3 N 4 -Based Catalystsmentioning

confidence: 99%

“…Hard templates like porous anodic metal oxide ( i.e. , alumina oxide (AAO) and ZnO) 82,112,113 and silica ( i.e. , SBA-15, SBA-16, FDU-12, and KIT-6) 114–116 are exhaustively used for the preparation of porous g-C 3 N 4 with different structures ( i.e.…”

Section: Graphitic Carbon Nitride Propertiesmentioning

confidence: 99%

Graphitic carbon nitride-based nanostructures as emergent catalysts for carbon monoxide (CO) oxidation

2023

View full text Add to dashboard Cite

show abstract

“…In the electrochemical and photochemical sensing described above, SACs play key roles in the information conversion based on the chemical reactions. However, light can generate electrical charges through certain semiconductor materials while the electrochemical reactions can excite the active materials into a state of luminescence on the lectrode surface, which are defined as PEC and ECL sensing, respectively 155 . In photoinduced ECL sensing, 156 information is communicated between the optical and electrical signals by taking advantage of the interactions between metals and supports 157 .…”

Section: Sacs Toward Biosensorsmentioning

confidence: 99%

Single‐atom metal‐nitrogen‐carbon catalysts energize single molecule detection for biosensing

Zhang

Chen

et al. 2023

InfoMat

View full text Add to dashboard Cite

Biosensors featuring single molecule detection present huge opportunities as well as challenges in food safety inspection, disease diagnosis, and environmental monitoring. Single-molecule detection is largely lacking of high enough activity, precision molecule selectivity, and understanding in the exact operating mechanism. Single-atom catalysts (SACs), especially those metals-nitrogen-carbon that mimic the natural metalloenzyme structure, and with well-defined metal atom bond configurations, high level of molecular selectivity, and easy fabrication, endow single molecule detections with practical-use feasibilities. The recent advances in singleatom catalysts also present new pathways in the key mechanism understandings. In this short review, we will first visit the brief history and advantages of SACs that have been explored only recently for moleculescale biosensors, where they are analogous and also differentiated from those nanozymes and natural metalloenzymes. Their applications in electrochemical, photochemical, and photoelectrochemical sensors are then discussed comprehensively by focusing on the different molecule-scale sensing modes in achieving local coordination-modulated signal amplifications. Finally, we identify new opportunities and challenges faced by these SACs-based single molecule detections in the further development of biosensors.

show abstract

“…Among these 2D nanomaterials, PCN nanosheets (NSs) with a π-conjugated planar topography formed by sp 2 bonded carbon and nitrogen are more economical, nontoxic, and environment friendly. Moreover, good thermodynamic and chemical stability, high fluorescence quantum yield and water dispersibility, and excellent biocompatibility make them highly favorable for fluorescent biosensing applications. , Based on the superior fluorescence-quenching ability and the different affinities toward ssDNA and dsDNA of PCN NSs, a few fluorescent biosensing platforms have been designed for the detection of multiple target DNA, ratiometric fluorescence detection of DNA and Hg 2+ , and intracellular microRNA imaging. − For example, Ju and co-workers proposed a ratiometric sensing strategy for the detection of ssDNA based on the photoexcited electrons from the fluorophore to the conductive band of PCN NSs . Two partial complementary ssDNA sequences with different lengths labeled with fluorescein (FAM) and X-rhodamine (ROX) were used as the fluorescent probes.…”

Section: Introductionmentioning

confidence: 99%

Enhanced Polymeric Carbon Nitride Nanosheet-Based Fluorescence for Biosensing Applications

Chen

Zhou

Chen

et al. 2023

ACS Appl. Nano Mater.

View full text Add to dashboard Cite

Two-dimensional (2D) nanomaterials have been extensively used as quenching platforms of fluorescently labeled oligonucleotides for the design of biosensors. However, not all fluorophore-labeled single-stranded DNA (ssDNA) is necessarily quenched after they are adsorbed on the surface of 2D nanomaterials. Herein, we discovered that the fluorescence of tetramethylrhodamine (TMR)-labeled ssDNA was not quenched but enhanced by polymeric carbon nitride nanosheets (PCN NSs). Effects of the fluorophore, oligonucleotide sequence, and the number of proximal G bases on the fluorescence of fluorophore-labeled ssDNA were investigated in the presence of PCN NSs. The fluorescence enhancement phenomena were not observable for fluorescein-and X-rhodamine-labeled ssDNA and other 2D nanomaterials such as graphene oxide and MoS 2 NSs. In the presence of PCN NSs, steric hindrance effect shields the photoinduced electron transfer quenching effect between TMR and proximal G bases, which may account for the fluorescence enhancement of TMR-labeled ssDNA adsorbed on PCN NSs. Benefiting from the fluorescence enhancement effect and the affinity change of PCN NSs to ssDNA probes upon hybridization with complementary ssDNA, a versatile ratiometric biosensing platform as a proof concept was demonstrated for the high sensitive fluorescence detection of ssDNA and microRNA.

show abstract

Graphitic carbon nitride-based nanoplatforms for biosensors: design strategies and applications

Cited by 26 publications

References 177 publications

Graphitic carbon nitride-based nanostructures as emergent catalysts for carbon monoxide (CO) oxidation

Graphitic carbon nitride-based nanostructures as emergent catalysts for carbon monoxide (CO) oxidation

Single‐atom metal‐nitrogen‐carbon catalysts energize single molecule detection for biosensing

Enhanced Polymeric Carbon Nitride Nanosheet-Based Fluorescence for Biosensing Applications

Contact Info

Product

Resources

About