Green and Efficient Synthesis of Mesoporous Sodalite Assisted by Persulfate or Peroxymonosulfate

Continuous-flow and safe synthesis of 3-amino-4-amidoximinofurazan

“…On the basis of the above proposed method, a series of optimization studies were reported aiming at finding the optimal process conditions to improve the purity and yield of AAOF. [9][10][11][12] Among them, Zhou 12 found that the yield of AAOF was greatly limited by the transformation from AAOF into the corresponding water-soluble sodium salts in alkaline solution. By adjusting the pH of the final reaction solution, an optimal AAOF yield of 95% was obtained.…”

“…Both nitrosation and oximation reactions are accompanied by a strongly exothermic effect, and the intermediate product of the oximation reaction, namely, 1,3-amino-trioxime propane, will precipitate during the feeding process, causing the liquid system to be sticky, which is unfavorable to heat removal. 10 In combination with the presence of a thermally unstable intermediate, hydroxylamine solution, 13 a runaway reaction is highly possible to occur when scaling up the AAOF synthesis process. Moreover, since the maximum allowable temperature of dehydration cyclization is the boiling point of the reaction solution (∼105 °C) in the batch reactor, the reaction rate is greatly limited, and subsequently the throughput is at a low level.…”