Abstract-Rising energy costs and climate change have led to an increased concern for energy-efficiency (EE). As Information and Communication Technology (ICT) is responsible for about 4% of total energy consumption worldwide, it is essential to devise policies aimed at reducing it. In this paper, we propose a routing and scheduling algorithm for a cloud architecture, which targets minimal total energy consumption by enabling switching off unused network and/or Information Technology (IT) resources, exploiting the cloud-specific anycast principle. A detailed energy model for the entire cloud infrastructure comprising wide area optical network and IT resources is provided. This model is used to make a single-step decision on which IT end points to use for a given request, including the routing of the network connection towards these end points. Our simulations quantitatively assess the EE algorithm's potential energy savings, but also assess the influence this may have on traditional Quality of Service parameters such as service blocking. Furthermore, we compare the one-step scheduling with traditional scheduling and routing schemes, which calculate the resource provisioning in a two-step approach (selecting first the destination IT end point, and subsequently using unicast routing towards it). We show that depending on the offered infrastructure load, our proposed onestep calculation considerably lowers the total energy consumption (reduction up to 50%) compared to the traditional iterative scheduling and routing, especially in low to medium load scenarios, without any significant increase in the service blocking.