Green oxygen power plants in the brain rescue neuronal activity

Abstract

HighlightsTranscardially injected microalgae accumulate in brain blood vessels of Xenopus Upon illumination, green algae and cyanobacteria robustly produce O 2 in the brain After hypoxic loss of brain function, photosynthetic oxygen rescues neural activity

Transcardial injection and vascular distribution of microalgae in Xenopus laevis as means to supply the brain with photosynthetic oxygen

“… Te, telencephalon; Di, diencephalon; OT, optic tectum; Cb, cerebellum; Hb, hindbrain. Adapted from Özugur et al. (2021) with permission under the CC BY-NC-ND license agreement.…”

“… (C) Setup for measurements of photosynthetic O 2 production upon illumination in isolated suspensions of microorganisms. (A–C) adapted from and Özugur (2021) and Özugur et al. (2021) , with permission under the CC BY-NC-ND license agreement.…”

“… (A–C) adapted from and Özugur (2021) and Özugur et al. (2021) , with permission under the CC BY-NC-ND license agreement.…”

“…This technology is potentially able to ameliorate consequences of hypoxia under pathological conditions. For complete details on the use and execution of this protocol, please refer to Özugur et al. (2021) .…”

“…For complete details on the use and execution of this protocol, please refer to Özugur et al. (2021) .…”