Green Synthesis and Antibacterial Properties of Silver Nanoparticles Using Sudanese &amp;lt;i&amp;gt;Azadirachta indica&amp;lt;/i&amp;gt; Leaves Extract

Alrasheid, Ayat Ahmed; Eltilib, Sahar Hussein; Ahmed, Sohail; Mohamed, Alaa Abdulmoneim; Widatalla, Hiba Abbas; Yassin, Layla Fathi; Ali, Maida Musa; Widdatallh, Marvit Osman

doi:10.11648/j.sr.20200801.13

Cited by 2 publications

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“…Over the years, it has attracted the attention of several researchers, in particular for its pulp which has many nutraceutical and medicinal properties (Acham et al, 2020;Alrasheid et al, 2019). Among these properties we have its ability to fight against hyperlipidemia, which is one of the major risk factors for cardiovascular diseases which are today the leading cause of death in the world (WHO, 2017).…”

Section: Introductionmentioning

confidence: 99%

Phenolic characterization and lipid lowering properties of powder fractions and ethanolic extract of Adansonia digitata pulp.

2022

Int. J. Biosci.

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This study aimed to evaluate the effect of controlled differential sieving treatment on the phenolic content and antihyperlipidemic activity of A.digitata pulp and compared it to the effect of ethanolic extract. For this purpose, powders with particle sizes ranging from 20 to 100 µm and above were produced and analyzed. As a first step, we identified and quantified the phenolic compounds present in the samples by chromatography in liquid phase coupled to a UV detector and mass spectrometry (LC-MS). Then, we evaluated the antihyperlipidemic activity of the different fractions in adult male rats at a dose of 250 mg/kg and compared them with those of unsieved powder and the lyophilized ethanolic extract. LC-MS analysis identified four compounds (quercetin, rutin, ferrulic acid and cafeic acid) in the different sample of A. digitata pulp powder. The granulometric class <50μm showed the best concentration, higher than those of the other granulometric class and crude powder. This fraction also showed content of phenolic compounds similar to those of ethanolic extract except cafeic acid which was more concentrated in the ethanolic extract. The antihyperlipidemic activity were significantly influenced (P <0.05) by particle sizes. The best activity was obtained from the <50μm µm fraction which was significantly (P <0.05) higher than the other fractions and the unsieved powder to improve the lipid parameters (TC, LDL-C, HDL-C and TG), transaminases (ALAT and ASAT) and creatinine. It showed similar activity to the ethanolic extract with the exception of LDL-C which is lower in this fraction. Controlled differential sieving process can be an alternative to ethanol extraction and may be an option to improve the content of phenolic compounds and antihyperlipidemic activity of plant powders.

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Section: Introductionmentioning

confidence: 99%

Phenolic characterization and lipid lowering properties of powder fractions and ethanolic extract of Adansonia digitata pulp.

2022

Int. J. Biosci.

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Antibacterial properties of silver nanoparticles greenly synthesized using guava fruit extract as a reducing agent and stabilizer

2022

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Green Synthesis and Antibacterial Properties of Silver Nanoparticles Using Sudanese <i>Azadirachta indica</i> Leaves Extract

Cited by 2 publications

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Phenolic characterization and lipid lowering properties of powder fractions and ethanolic extract of Adansonia digitata pulp.

Phenolic characterization and lipid lowering properties of powder fractions and ethanolic extract of Adansonia digitata pulp.

Antibacterial properties of silver nanoparticles greenly synthesized using guava fruit extract as a reducing agent and stabilizer

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